Abstract
A novel coumarin derivative (7e) was identified as a dual CDK6/VEGFR-2 inhibitor with potent enzymatic activity, apoptosis induction, cell cycle arrest, and anti-migratory effects, supported by docking, molecular dynamics, and DFT studies.
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Privacy-aware community infrastructureHazem Elkady, Walid E. Elgammal, Ibrahim H. Eissa, Hanan A. Al-ghulikah, Ghalbaa N. Alshahrani, Ahmed M. Metwaly, Eslam B. Elkaeed
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