Unifocal amyloidosis: a rare cause of spinal cord compression

A 75-year-old man presented with a 3-month history of progressive paraparesis due to an extradural mass causing cord compression at the T7 level of the thoracic spine. He underwent decompressive surgery, and later vertebrectomy and cage fixation. Histologically, the lesion was a localized mass of amyloid associated with a clonal plasma cell infiltrate. Localized 'amyloidomas' of the spine are rare, evolve slowly and often have a good prognosis following surgery.