Long-term SBP time in target and risk of cardiovascular events in older adults: a secondary analysis of the ASPREE cohort

Abstract Background BP time in target range (TTR) predicts cardiovascular disease (CVD) in high-risk populations; however, TTR’s predictive utility in older adults without prior CVD is uncertain. Methods We performed a post hoc analysis of the ASPirin in Reducing Events in the Elderly trial and its observational follow-up. SBP TTR for Results Among 16,730 predominantly White Australian adults (mean age, 74 years) followed for a mean of 7.7 years after TTR estimation, 100% TTR Conclusions Longer SBP TTR was associated with reduced risk of cardiovascular events in older adults, underscoring the importance of sustained BP control with aging.