Abstract
Tamaki Suganuma, Jerry L Workman
Abstract
Authors
Institutions
No ROR-resolved institution is linked to this work yet.
Provenance
crossref
Confidence 100%
pubmed
Confidence 98%
europepmc
Confidence 96%
unpaywall
Confidence 95%
datacite
Confidence 0%
No local reference links have been materialized yet.
No local citing links have been materialized yet.
Clinical review: oxygen as a signaling molecule
10.1186/cc9185 · 2010
Cell energy metabolism: an update
10.1016/j.bbabio.2020.148276 · 2020
Chromatin and metabolism
10.1146/annurev-biochem-062917-012634 · 2018
The multifaceted contributions of mitochondria to cellular metabolism
10.1038/s41556-018-0124-1 · 2018
Chromatin balances cell redox and energy homeostasis
10.1186/s13072-023-00520-8 · 2023
Free radicals and antioxidants in normal physiological functions and human disease
10.1016/j.biocel.2006.07.001 · 2007
Histone H3 threonine 11 phosphorylation by Sch9 and CK2 regulates chronological lifespan by controlling the nutritional stress response
10.7554/elife.36157 · 2018
Oxidative stress: harms and benefits for human health
10.1155/2017/8416763 · 2017
Thriving in oxygen while preventing ROS overproduction: no two systems are created equal
10.3389/fphys.2022.874321 · 2022
A functional account of stimulation-based aerobic glycolysis and its role in interpreting BOLD signal intensity increases in neuroimaging experiments
10.1016/j.neubiorev.2023.105373 · 2023
Macrophages, metabolites, and nucleosomes: chromatin at the intersection between aging and inflammation
10.3390/ijms221910274 · 2021
Nutriepigenomics in environmental-associated oxidative stress
10.3390/antiox12030771 · 2023
Altered transposon element-derived genes distort oxygen-free radical scavenger systems in FXD
10.1093/narmme/ugag010 · 2026
Variants of core histones and their roles in cell fate decisions, development and cancer
10.1038/nrm.2016.166 · 2017
Metabolism and regulation of canonical histone mRNAs: life without a poly(a) tail
10.1038/nrg2438 · 2008
Chromatin challenges during DNA replication and repair
10.1016/j.cell.2007.01.030 · 2007
ATP-dependent chromatin remodeling shapes the DNA replication landscape
10.1038/nsmb.1419 · 2008
Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes
10.1038/nrm.2017.26 · 2017
Regulating the chromatin landscape: structural and mechanistic perspectives
10.1146/annurev-biochem-051810-093157 · 2014
Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes
10.1016/j.cell.2013.07.011 · 2013
Nucleosome remodeling and epigenetics
10.1101/cshperspect.a017905 · 2013
Persistent site-specific remodeling of a nucleosome array by transient action of the SWI/SNF complex
10.1126/science.273.5274.513 · 1996
Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex
10.1126/science.8016655 · 1994
Structure and mechanism of the chromatin remodelling factor ISW1a
10.1038/nature09947 · 2011
ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps
10.1016/j.cell.2012.12.040 · 2013
Yeast Isw1p forms two separable complexes in vivo
10.1128/mcb.23.1.80-91.2003 · 2003
Histone octamer structure is altered early in ISW2 ATP-dependent nucleosome remodeling
10.1016/j.celrep.2019.05.106 · 2019
Chromatin remodeling through directional DNA translocation from an internal nucleosomal site
10.1038/nsmb973 · 2005
Regulation of DNA translocation efficiency within the chromatin remodeler RSC/Sth1 potentiates nucleosome sliding and ejection
10.1016/j.molcel.2016.03.032 · 2016
ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding
10.1038/nsmb.1397 · 2008
CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion
10.1038/s41586-023-05961-5 · 2023
Targeted degradation of CTCF decouples local insulation of chromosome domains from genomic compartmentalization
10.1016/j.cell.2017.05.004 · 2017
Human Condensin I and II drive extensive ATP-dependent compaction of nucleosome-bound DNA
10.1016/j.molcel.2020.04.026 · 2020
Topological domains in mammalian genomes identified by analysis of chromatin interactions
10.1038/nature11082 · 2012
Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
10.1016/j.cell.2025.10.013 · 2025
CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming
10.1016/j.celrep.2022.110626 · 2022
CTCF regulates global chromatin accessibility and transcription during rod photoreceptor development
10.1073/pnas.2416384122 · 2025
The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
10.1016/s0092-8674(00)81967-4 · 1999
ISW1a modulates cohesin distribution in centromeric and pericentromeric regions
10.1093/nar/gkad612 · 2023
Variations in flanking or less conserved positions of Reb1 and Abf1 consensus binding sites lead to major changes in their ability to modulate nucleosome sliding activity
10.1186/s40659-025-00627-0 · 2025
The regulation and functions of DNA and RNA G-quadruplexes
10.1038/s41580-020-0236-x · doi-reference
Structural insight into nucleosome transcription by RNA polymerase II with elongation factors
10.1126/science.aav8912 · doi-reference
Structural basis of the nucleosome transition during RNA polymerase II passage
10.1126/science.aau9904 · doi-reference
NF-κB regulation: lessons from structures
10.1111/j.1600-065x.2012.01097.x · doi-reference
Structural insights into p300 regulation and acetylation-dependent genome organisation
10.1038/s41467-022-35375-2 · doi-reference
The molecular basis for cellular function of intrinsically disordered protein regions
10.1038/s41580-023-00673-0 · doi-reference
RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation
10.1038/s41594-018-0102-0 · doi-reference
MYC acetylated lysine residues drive oncogenic cell transformation and regulate select genetic programs for cell adhesion-independent growth and survival
10.1101/gad.350736.123 · doi-reference
Chromosome 8q24-associated cancers and MYC
10.1177/1947601910381380 · doi-reference
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer
10.1038/ng.403 · doi-reference
Brd4 coactivates transcriptional activation of NF-κB via specific binding to acetylated RelA
10.1128/mcb.01365-08 · doi-reference
The BRD4-nucleosome interaction is enhanced modestly and non-selectively by histone acetylation
10.1093/nar/gkaf1406 · doi-reference
Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1
10.1074/jbc.m113.523019 · doi-reference
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
10.1073/pnas.1433065100 · doi-reference
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis
10.1016/j.molcel.2014.08.024 · doi-reference
The Mediator complex: a central integrator of transcription
10.1038/nrm3951 · doi-reference
Enhancer RNA (eRNA) in human diseases
10.3390/ijms231911582 · doi-reference
A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells
10.1016/j.cell.2011.03.042 · doi-reference
A phase separation model for transcriptional control
10.1016/j.cell.2017.02.007 · doi-reference
Viscoelastic phase separation in biological cells
10.1038/s42005-022-00947-7 · doi-reference
Spatially non-uniform condensates emerge from dynamically arrested phase separation
10.1038/s41467-023-36059-1 · doi-reference
Putting the squeeze on phase separation
10.1021/jacsau.1c00443 · doi-reference
Inflammation-sensitive super enhancers form domains of coordinately regulated enhancer RNAs
10.1073/pnas.1424028112 · doi-reference
The solid and liquid states of chromatin
10.1186/s13072-021-00424-5 · doi-reference
Engineering biological C-H functionalization leads to allele-specific regulation of histone demethylases
10.1021/jacs.6b08653 · doi-reference
JMJD family proteins in cancer and inflammation
10.1038/s41392-022-01145-1 · doi-reference
Mitochondrial protein lipoylation and the 2-oxoglutarate dehydrogenase complex controls HIF1α stability in aerobic conditions
10.1016/j.cmet.2016.09.015 · doi-reference
2-oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases
10.1038/s41467-021-26673-2 · doi-reference
2-oxoglutarate-dependent dioxygenases in cancer
10.1038/s41568-020-00303-3 · doi-reference
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
10.1126/science.aaw1026 · doi-reference
Hypoxia induces rapid changes to histone methylation and reprograms chromatin
10.1126/science.aau5870 · doi-reference
Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase
10.1038/nsmb1273 · doi-reference
Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase
10.1042/bj20121155 · doi-reference
Roles of HIF and 2-oxoglutarate-dependent dioxygenases in controlling gene expression in hypoxia
10.3390/cancers13020350 · doi-reference
The activity of JmjC histone lysine demethylase KDM4A is highly sensitive to oxygen concentrations
10.1021/acschembio.6b00958 · doi-reference
Histone demethylation by a family of JmjC domain-containing proteins
10.1038/nature04433 · doi-reference
Critical roles of the cysteine-glutathione axis in the production of gamma-glutamyl peptides in the nervous system
10.3390/ijms24098044 · doi-reference
Histone H3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure
10.1089/ars.2012.5021 · doi-reference
Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein
10.1016/j.molcel.2011.02.018 · doi-reference
Methionine metabolism in health and cancer: a nexus of diet and precision medicine
10.1038/s41568-019-0187-8 · doi-reference