Capsaicin ameliorates irritable bowel syndrome in a mouse model by restoring intestinal barrier function and promoting gut microbial homeostasis

Geyujia Zhou; Zifan Shen; Yin Hong

doi:10.1097/cm9.0000000000003750

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Capsaicin ameliorates irritable bowel syndrome in a mouse model by restoring intestinal barrier function and promoting gut microbial homeostasis

Geyujia Zhou, Zifan Shen, Yin Hong

Chinese Medical Journal2025doi:10.1097/cm9.0000000000003750

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Geyujia Zhou#2 Zifan Shen#3 Yin Hong#4

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External reference records

Irritable bowel syndrome: Treatment based on pathophysiology and biomarkers

10.1136/gutjnl-2022-328515 · 2023

Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection

10.1016/j.cell.2022.09.024 · 2022

The comprehensive pathophysiological changes in a novel rat model of postinflammatory visceral hypersensitivity

10.1096/fj.201901489r · 2019

Gut microbiota mediates the protective effects of dietary capsaicin against chronic low-grade inflammation and associated obesity induced by high-fat diet

2017

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