Abstract
Purpose:
To evaluate the long-term visual outcomes, recurrence, complication rate, and systemic associations of persistent placoid maculopathy. We also aimed to identify predictors of final visual acuity.
Methods:
This study combined a retrospective multicenter case series from three tertiary referral centers with a systematic review of the literature. Inclusion criteria were bilateral placoid macular lesions with characteristic multimodal imaging findings and a minimum follow-up of 23 months. Visual acuity, systemic associations, complications, recurrence, and treatments were assessed.
Results:
Twenty-three patients (46 eyes) were included, six patients from our centers and 17 patients from the literature. The median follow-up was 3.75 years. Severe visual loss (P
= 0.014).
Conclusion:
Persistent placoid maculopathy presents a high complication rate and poor visual prognosis. Systemic treatment was significantly associated with better final visual acuity in our study.