Abstract
Purpose:
To analyze the efficacy and safety of optical coherence tomography angiography-based navigated laser treatment in central serous chorioretinopathy (CSCR) complicated by choroidal neovascularization (CNV).
Methods:
This study included consecutive patients with neovascular nonresolving CSCR who received en face OCT-based navigated laser treatment without fluorescein angiography or were observed untreated for at least 6 months. In all treated cases, the area of the double-layer sign with flow signal displayed with structural en face OCT image was treated with microsecond pulsing laser (up to three sessions), direct continuous wave focal laser photocoagulation, or their consecutive combination. Main outcome measure was complete resolution of subretinal fluid.
Results:
Sixty-seven eyes of 67 patients (28 male patients, 41.8%) with a mean age of 57.5 ± 7.7 years were included in the treatment group. Thirty eyes of 30 patients (14 male patients (46.7%), mean age 58.1 ± 6.9 years) were included in the control group. Complete resolution of subretinal fluid was achieved in 32 eyes (47.8%) in the treatment group compared with none in the control group (
P
Conclusion:
Optical coherence tomography angiography-guided laser treatment is a viable and safe option in the management of CSCR complicated by CNV, mostly effective in cases with extrafoveal CNV.