Cancer Predisposition Syndromes in Children: Who, When, and How to Screen?

Kin Fen Kevin Fung; Caroline Rutten; Vivek B. Pai; Elaine YL Kan; Suzanne Laughlin; Yin Ting Chiu; Eman Marie; Birgit Ertl-Wagner; Stephan D. Voss; Lisa J. States; Andrea S. Doria; Mary-Louise C. Greer

doi:10.1148/rg.260022

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Cancer Predisposition Syndromes in Children: Who, When, and How to Screen?

Kin Fen Kevin Fung, Caroline Rutten, Vivek B. Pai, Elaine YL Kan, Suzanne Laughlin, Yin Ting Chiu, Eman Marie, Birgit Ertl-Wagner, Stephan D. Voss, Lisa J. States, Andrea S. Doria, Mary-Louise C. Greer

RadioGraphics2026doi:10.1148/rg.260022

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Abstract

In children with cancer predisposition syndromes, familiarity with syndrome-specific protocols and characteristic tumor imaging features, adoption of child-centered imaging strategies, and a coordinated multidisciplinary approach are essential to optimize outcomes and minimize screening-related harm.

Authors

Kin Fen Kevin Fung#1 Caroline Rutten#2 Vivek B. Pai#4 Elaine YL Kan#5 Suzanne Laughlin#6 Yin Ting Chiu#7 Eman Marie#8 Birgit Ertl-Wagner#9 Stephan D. Voss#11 Lisa J. States#12

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10.1038/nature25480

10.1158/1078-0432.ccr-25-0423

10.1148/rg.311105099

10.1016/s1470-2045(16)30249-2

10.1007/s00247-021-05023-w

10.1007/s10689-016-9964-7

10.1158/1078-0432.ccr-25-0597

10.1007/s00247-021-05044-5

10.1038/gim.2015.30

10.1038/s41591-024-03056-w

10.1001/jamaoncol.2021.4536

10.1002/pbc.28758

Cancer Predisposition Syndromes in Children: Who, When, and How to Screen?

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