Abstract
Molluscum contagiosum and human papillomavirus (HPV) are very common cutaneous infections with worldwide distribution, yet treatment options remain limited. Traditional therapies are invasive and have a high rate of recurrence, and newer topical agents available are costly. Here I discuss evidence supporting the hypothesis that the aluminum-based salts, utilized in the antiperspirant industry since the early 1900s, could have a therapeutic effect on skin lesions due to molluscum contagiosum, HPV and possibly other viruses. Clinical trials in this area are needed.