Abstract
:
ype 1 diabetes is characterized by an autoimmune β-cell destruction resulting in endogenous insulin
deficiency, potentially leading to micro- and macrovascular complications. Besides an exogenous insulin therapy
and continuous glucose monitoring, physical exercise is recommended in adults with type 1 diabetes to improve
overall health. The close relationship between physical exercise, inflammation, muscle contraction, and macronutrient
intake has never been discussed in detail about type 1 diabetes. The aim of this narrative review was to
detail the role of physical exercise in improving clinical outcomes, physiological responses to exercise and different
nutrition and therapy strategies around exercise.
:
Physical exercise has several positive effects on glucose uptake and systemic inflammation in adults with type 1
diabetes. A new approach via personalized therapy adaptations must be applied to target beneficial effects on
complications as well as on body weight management. In combination with pre-defined macronutrient intake
around exercise, adults with type 1 diabetes can expect similar physiological responses to physical exercise, as
seen in their healthy counterparts.
:
This review highlights interesting findings from recent studies related to exercise and type 1 diabetes. However,
there is limited research available accompanied by a proper number of participants in the cohort of type 1 diabetes.
Especially for this group of patients, an increased understanding of the impact of physical exercise can improve
its effectiveness as an adjuvant therapy to move (forward).