Abstract
It has been conducted a study of identify population of spermatogenic cells of mice after induction Durian (Durio zibethinus Murr.) bark extract. This research used completely randomized design with five treatments i.e. control without treatment; control with aquadest; 5 percent durian bark extract; 10 percent; and 20 percent with five repetitions for each treatment. Extract was given per oral in volume dose of 0,5 ml/ 25–30 g/BW per day during 36 days. The result of this study showed that durian bark extracts caused significantly decrease of population of spermatogenic cells in concentrate 5, 10, and 20 percent.