Abstract
Peptic ulcer disease is the common gastrointestinal disorder, which affects the high number ofpeople during their life. The present study was carried out among 267 patients with different uppergastrointestinal symptoms, at the Department of Endoscopy, Shahid Dr.Khalid Hospital/in Koya cityduring 1/2018-1/2019, all patients were assessed endoscopically and biopsies from both antral andbody mucosa were taken for histopathological examination. The aim of this study was to determinethe spectrum of histopathological biopsies of the gastric region with the distribution of peptic ulcerbiopsies according to age and sex in Koya city, Kurdistan Region, Iraq. The study showed normalgastric mucosa histopathologically in 22 (8.24%) cases and 245 (91.76%) abnormal gastric mucosahistopathologically. Gastritis histopathologically was seen in 217 (81.27%) of cases, chronic gastritisrepresented the highest relative frequency in this histopathologically diagnosed patients, where it wasseen in 65.89% of the cases and acute gastritis was detected in 34.10% of the cases. Helicobacterpylori was detected in 82.77% of patients. A significant association was detected between chronicgastritis and H. pylori infection.