Abstract
BACKGROUND: Androgenetic alopecia is a widespread disorder that presents therapeutic challenges due to patients' inflated expectations, low treatment compliance associated with inconvenient topical application, and concerns regarding adverse effects. Therefore, investigating the efficacy of non-drug multi-component agents for managing hair loss and stimulating hair growth appears highly relevant.
AIM: Evaluation of the efficacy of a corrective and stimulating serum combining a minoxidil derivative and high-concentration niacinamide in women with androgenetic alopecia.
METHODS: The study involved 38 female patients who applied the serum daily for 4 months. The outcomes were assessed clinically and using phototrichogram analysis.
RESULTS: Upon completion of the treatment course, clinical recovery was observed in 25 patients (65.8%), significant improvement — in 4 (10.5%), and improvement — in 3 (7.9%). No effect was reported in 6 cases (15.8%). The proportion of telogen hair normalized (≤ 10%) in 27 women (71.1%).
CONCLUSION: The multi-component serum applied in the study showed high efficacy and good tolerability in the treatment of female androgenetic alopecia. Its ease of use promotes better treatment compliance, allowing this product to be recommended for long-term application in the comprehensive management of this condition.