Abstract
Secondary lymphedema is a chronic condition resulting from acquired damage to the lymphatic system, leading to impaired lymphatic drainage and progressive interstitial fluid accumulation. Poorly controlled diabetes represents a significant predisposing factor, contributing to the development and progression of lymphedema through microvascular dysfunction, recurrent skin infections, delayed wound healing, and chronic inflammation. We report on the case of a patient with poorly followed diabetes for eight years who developed secondary lymphedema of the lower limb. This case highlights the diagnostic challenges related to the coexistence of diabetic complications, as well as the therapeutic difficulties encountered in the context of long-standing glycemic imbalance. Early and multidisciplinary management of diabetes is essential to prevent the onset and progression of secondary lymphedema.