Abstract
In this meta-analysis, we performed a literature search for articles relating to asymptomatic monkeypox virus (MPXV) detections published worldwide during May 12, 2022-September 13, 2024. The primary outcome was to determine the pooled prevalence of asymptomatic MPXV detections. We conducted a random-effects analysis that yielded a final pooled prevalence of 1.0% (95% prediction interval 0.1%-11.2%). Results did not substantially differ by geographic region or study design. Although those findings are reassuring, we did not evaluate infectivity or transmission potential among asymptomatic persons. MPXV continues to circulate globally; the viral dynamics that enable its persistence remain poorly understood and merit further study.