Effect of Drug-Coated Balloons on Recurrent Venous Hypertension Due to Central Venous Lesions in Patients with Hemodialysis Vascular Access

Objectives This study aimed to evaluate the efficacy of drug-coated balloons (DCBs) for symptomatic and recurrent central venous lesions (including in-stent restenosis and occlusion) in patients undergoing hemodialysis.Methods Twenty-seven patients treated with DCBs for symptomatic central venous lesions between June 2021 and September 2025 were included. We examined the overall efficacy of DCBs, the outcomes of repeated use, and factors affecting patency.Results Target lesion patency at 6 months was significantly improved following initial DCB use (77% vs. 30% prior to DCB use, p Conclusions DCBs demonstrated satisfactory efficacy for recurrent central venous lesions, which was maintained with repeated use. Additionally, pre-dilatation using PCBs showed a trend toward improved patency rates. (This is a translation of Jpn J Vasc Surg 2026; 35: 23-28.).