Abstract
Physical activity and structured exercise are essential components of the management of diabetes and obesity (Moser et al., 2020)(Davies et al., 2022). Nevertheless, many people do not achieve recommended activity levels, and the translation of exercise recommendations into everyday life remains challenging. Digital solutions may help to overcome this gap by providing personalised guidance, continuous feedback and scalable support beyond traditional clinical settings (Moser et al., 2025).
This keynote will explore how digital health applications, including Digital Health Applications (DiGAs), can be integrated into exercise therapy for people with type 2 diabetes and obesity (Kannenberg et al., 2026). Evidence from clinical studies will illustrate how app-based lifestyle interventions can combine physical activity promotion, nutritional support, continuous glucose monitoring and behavioural strategies to improve metabolic outcomes and facilitate sustainable lifestyle changes. For people with type 1 diabetes, the presentation will focus on the interaction between exercise, continuous glucose monitoring and automated insulin delivery (Zivkovic et al., 2026). Current developments towards fully closed-loop systems will be discussed, with particular attention to how glucose data, insulin delivery, physical activity, meals and contextual information can be merged into integrated decision-support systems (Bünzel et al., 2026). Such approaches may reduce the burden of exercise-related glucose management and enable safer and more personalised participation in physical activity.
Finally, the emerging role of artificial intelligence and large language models in diabetes, obesity and exercise research will be addressed. Potential applications include the analysis of complex multimodal datasets, personalised exercise recommendations, clinical decision support and the development of new research approaches. Alongside these opportunities, important limitations relating to data quality, validation, transparency and clinical responsibility will be considered.
Overall, digital therapeutics, connected diabetes technologies and artificial intelligence have the potential to transform exercise therapy from a largely standardised intervention into a more personalised, adaptive and continuously supported component of diabetes and obesity care. Their successful implementation may help translate scientific evidence into accessible, safe and sustainable real-world physical activity support by bridging the gap between clinical recommendations and daily life, while enabling more individualised guidance, continuous feedback and informed therapeutic decision-making.
References
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