Abstract
Purpose: This study aimed to determine the distribution of S.aureus strains isolated from clinical specimens in a training and research hospital according to clinics and specimen types and evaluate the change in antibiogram results over the years. Materials and Methods: S. aureus strains isolated from various clinical samples in the Microbiology Laboratory of Ordu University Training and Research Hospital between May 2021 and May 2024 were included in the study. Identification and antibiogram results of the isolates were evaluated retrospectively.Results: In our study, 143 (24.2%) of 592 isolates were identified as MRSA and 449 (75.8%) as MSSA. The highest rate of growth was observed in samples from outpatient clinics, and both MRSA and MSSA strains were most frequently isolated from urine samples. The most resistant antimicrobials for MRSA were tetracycline (54.5%), clindamycin (41.3%) and erythromycin (40.6%) while for MSSA erythromycin (21.3%), tetracycline (20.6%) and clindamycin (18.6%). No resistance to daptomycin, linezolid, teicoplanin and vancomycin was found in both strains. Conclusion: Although no glycopeptide resistance was found in S. aureus strains isolated from various cultures in our hospital, TMP/SXT, moxifloxacin, gentamicin and amikacin can be used in the treatment of both MRSA and MSSA. The results of antimicrobial susceptibility tests are important in the selection of appropriate treatment.