Histopathological Study of Ovarian Cysts in Derna

Ovarian cysts, which are sacs filled with fluid located in the ovaries, represent the primary reason for enlarged ovaries, impacting approximately 20% of women who experience a pelvic mass at least once during their lifetime. The present work was carried out to focus on the frequency, gross appearance and histopathological features of each type of ovarian cysts in Derna-City East of Libya. This work included 54 cases of ovarian cysts, out of 338 samples submitted to Noor-AL-Huda Medical Center Pathology Laboratory in Derna City –East of Libya during the period between January 2022 and April 2023, samples were formalin fixed, processed, then H &E sections were obtained for histologic diagnosis and subtyping. The age of patients ranges from 5 – 68 years, the predominant age group was 30– 39 years, 26 (48.14%) were on the right side, 23(42.59%) were on the left side, 5(9.25%) were bilateral. The commonest presenting symptoms were both incidental in 21(38.8%) and pain in 18(33.33%); the cyst mainly obtained from Cystectomy operation 39 (72.22%). Gross appearance of each type was studied. Out of the included 54 ovarian cysts 29 (53.70%) were non –neoplastic and25 (46.29%) were neoplastic. Follicle cysts represented (37.93%) of the non-neoplastic lesions, while serous cyst adenoma represented (40%) of the neoplastic lesions. We concluded that non-neoplastic cysts are the most common types of ovarian cysts. Among non-neoplastic ovarian cysts, the functional cysts including follicular and corpus luteal cysts were the most common, while serous cysts and teratomas are the common neoplastic cysts. Most ovarian cysts are found on the right side. Histopathological examination is essential for accurate diagnosis and proper management of ovarian cysts.