Cushing syndrome is a clinical condition characterized by elevated body cortisol level with its attendant clinical features. It's relatively rare. We report this clinical condition due to its rarity and our objective was to illustrate the clinical features, diagnosis and the its successful management. A 23-year-old Nigerian woman was seen at the surgical outpatient department of federal medical centre Dutse, Jigawa State following a referral from the general outpatient department of the same institution with 2 years history of amenorrhea, excessive weight gain and hirsutism. The clinical examination was remarkable for raised blood pressure and Cushingoid appearance. Besides, biochemical and radiological evaluation were suggestive of right adrenal hypercortisolism. She had open right adrenalectomy and was discharged satisfactorily symptoms free with clinical follow that has been uneventful. We have reported our experience on the successful management of a rare case of Cushing syndrome secondary to adrenal adenoma.
