Prevalence of Toxoplasma gondii and Cytomegalovirus in Sera of Aborted Women in Zawia City

Toxoplasmosis is caused by the parasite Toxoplasma gondii. This disease is widespread and is considered a zoonotic disease. Infection with this disease leads to stillbirth, miscarriage, or a birth defect during pregnancy. Aim of the study is to determine the seroprevalence of Toxoplasma gondii in the city of Zawia. Over ten months Two hundred and eleven serum samples were collected from pregnant women To be examined for Toxoplasma gondii and cytomegalovirus at Al-Zawiya Hospital, Al-Zawiya city, Libya, and the Toxoplasma gondii parasite and cytomegalovirus were examined. The majority of aborted women were in the age group of 21-30 years (53.1%), followed by the 31-40 years age group (31.7%). Toxoplasmosis infection was more prevalent (32.7%) than cytomegalovirus (CMV) infection (15.2%), with a relatively low co-infection rate (6.6%). IgG (past/chronic infection) was present in 50.7% of cases, and IgM (recent/acute infection) in 59.2%. CMV: IgG was present in 35.5% of cases, and IgM in 69.7%. No significant association between toxoplasmosis IgG and CMV IgG. Significant association between toxoplasmosis IgG and CMV IgM, indicating a relationship between past/chronic toxoplasmosis and recent CMV infection. Highly significant association between toxoplasmosis IgM and CMV IgG, suggesting a link between recent toxoplasmosis and past/chronic CMV infection. Highly significant association between toxoplasmosis IgM and CMV IgM, indicating a strong relationship between recent infections of both pathogens. A serological screening program for early detection of toxoplasmosis and cytomegalovirus (CMV) infection in pregnant women and aborted women in Libya is considered essential to avoid all causes that pose problems for women.