Abstract
The present study aimed to synthesize the CuO-MCM-41-Ag nanocomposites by hydrothermal method and evaluate their antibacterial activity by disc diffusion method. The synergistic effects of the transition metal-based nanocomposites are supposed to possess highly strong antimicrobial actions. SEM and TEM analyzed the morphological features of the synthesized Copper xide-MCM-41-silver nanocomposites. According to these morphological analyses, the biosynthesized CuO-MCM-41-silver nanocomposites are composed of regularly distributed hexagonal-shaped particles in aggregated form. The crystallinity of the prepared nanocomposites was confirmed through the XRD technique. From the FTIR results, the peaks obtained are closely Si-OH deformational vibrations, stretching vibrations of the surface Si-O2 groups, and various other groups. The antibacterial activity of nanocomposites was evaluated on both Gram-negative and Gram-positive bacteria. It was monitored that the MIC of Staphylococcus aureus, Bacillus aureus, Pseudomonas aeruginosa, and Escherichia coli was 0.135 mL-1. The nanocomposites synthesized by the hydrothermal study were good antibacterial against specific gram-positive and gram-negative bacterial strains.