Abstract
The study investigated the efficacy of ten anti- hypertensive drugs as declared by their users.
The data for this study were sourced through a carefully structured questionnaire and
administered to 455 respondents at four strategic locations in Rivers State of Nigeria; (Emohua,
Ahoada, Khana and Etche). The variables were separated into “Factors” and “Runs” and twolevel supersaturated designs (SSDs) were considered and coded as -1 and 1 signifying low and
high levels respectively. The study also recognized a well-known criterion for evaluating the
efficacy of supersaturated design (SSD); E(S2
).
The drugs with equivalent efficacy levels were merged and represented by the higher or lower of
them all depending on the case. The repeated or duplicated experimental “Runs” (drugs) were
interchanged for “Factors” and were eliminated to allow for only a unique column thereby
preserving orthogonality principle. Thus, with the drugs as “Factors” we were able to obtain 4 x
6 design matrix representing 4 “Runs” AND 6 “Factors”. The study identified the most “active
factor” given the 6 “factors” (the most efficacious) of the drugs.