Abstract
Some bioactive nutrient chemical composition and effect of Datura stramonium leaf extract on body weight using Wistar albino rats were investigated using standard methods. D. stramonium leaves were procured from Rhema University school farm and processed for further studies. Some amino acids observed in the sample were lysine (3.16±0.12 g/100g protein), threonine (2.27±0.14 g/100g protein), glutamic acid (10.94±0.15 g/100g protein), and proline (1.62±0.13 g/100g protein). The amino acid groups of the leaf sample showed a Total Acidic Amino Acid (TAAA) of 18.04 g/100g protein (32.19%), Total Neutral Amino Acid (TNAA) of 14.38 g/100g protein (25.66%) and Total Basic Amino Acid (TBAA) of 11.00 g/100g protein (19.63%). Lauric acid, stearic acid and linolenic acids were among the fatty acids observed in D. stramonium in this study. The leaf extract showed significantly (p<0.05) reduced effects on weight and some visceral organs in Wistar albino rats. These effects could be due to the presence of these bioactive compounds observed in the plant. This study has shown some bioactive nutrient chemical composition and effect of D. stramonium leaf extract on body weight using Wistar albino rats.