Abstract
Background: Microneedling was initially introduced for skin rejuvenation. This review
analyzes the current literature on microneedling techniques, efficacy, and
safety for vitiligo treatment.
Methods: An extensive PubMed search was performed to identify literature on
microneedling therapy for vitiligo. Case reports, case series, and clinical
trials were included.
Results: All 14 articles evaluated showed improvement of lesions after microneedling
treatment. Combination of microneedling and topical tacrolimus, 5-FU,
topical calcipotriol and betamethasone, NB-UVB with or without PDT, and
triamcinolone acetonide solution yielded more efficacy than microneedling
monotherapy.
Conclusion: Microneedling is a safe and efficient technique and an adjuvant treatment for
vitiligo treatment.