Abstract
Pilomatricoma is a benign skin tumor derived from the hair follicle. It has a
varied etiology, and the traumatic one is often described as a triggering
factor. The surgical treatment is curative and, therefore, the choice. We report
a case of an atypical clinical presentation pilomatricoma – an ulcerated nodule
topped by a central hematic crust, with peripheral telangiectasias probably
triggered by the HPV vaccination. The ultrasound examination suggested the
possibility of a chronic inflammatory granuloma, although the histopathological
examination was definitive and confirmed the diagnosis of pilomatricoma.