Congenital gastric angiomatosis presenting as gastrointestinal bleeding in an Infant under 6 months of age: Two case reports and Review of the literature

We report a rare cause of gastrointestinal bleeding in two infants under 6 months of age, both presenting with hematemesis and melena without other apparent skin lesions. Endoscopic examinations revealed flat, diffuse, active mucosal bleeding due to petechial lesions of the fundus in one infant and of the antrum in the other, suggestive of congenital gastric angiomatosis. The first patient received systemic hemostatic therapy and gastric protection with good clinical outcome. The second patient, who had a more persistent bleeding syndrome, was treated with hemostatic therapy, gastric protection, a proton pump inhibitor, and a beta-blocker, with good clinical resolution of symptoms.