Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Understanding the link between cancer and neurodegeneration. Local targets link to admitted publications; unresolved targets remain external evidence.
Citron kinase is required for postnatal neurogenesis in the hippocampus
10.1159/000096216 · 2007 · External reference
Neoplasms of the central nervous system
2008 · External reference
Cell cycle markers in the hippocampus in Alzheimer's disease
10.1007/s004010050665 · 1997 · External reference
Expression of cell division markers in the hippocampus in Alzheimer's disease and other neurodegenerative conditions
10.1007/s004010050617 · 1997 · External reference
Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain
10.1523/jneurosci.18-08-02801.1998 · 1998 · External reference
Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease
1997 · External reference
Ki-67 immunoreactivity in Alzheimer's disease and other neurodegenerative disorders
10.1097/00005072-199505000-00002 · 1995 · External reference
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease
10.1073/pnas.0611671104 · 2007 · External reference
Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta
10.1006/exnr.2002.8047 · 2003 · External reference
Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases
10.1016/s0197-4580(00)00221-9 · 2000 · External reference
Mitotic phosphoepitopes precede paired helical filaments in Alzheimer's disease
10.1016/s0197-4580(98)00071-2 · 1998 · External reference
Mitochondrial abnormalities in Alzheimer's disease
10.1523/jneurosci.21-09-03017.2001 · 2001 · External reference
Tumorigenesis and neurodegeneration: two sides of the same coin?
10.1002/bies.20784 · 2008 · External reference
DNA replication precedes neuronal cell death in Alzheimer's disease
10.1523/jneurosci.21-08-02661.2001 · 2001 · External reference
Problem situations in the treatment of paralysis agitans
10.1001/jama.1954.02950070008003 · 1954 · External reference
Prospective case–control study of nonfatal cancer preceding the diagnosis of Parkinson's disease
10.1007/s10552-007-9005-9 · 2007 · External reference
A prospective cohort study of cancer incidence following the diagnosis of Parkinson's disease
10.1158/1055-9965.epi-07-0038 · 2007 · External reference
Risk of cancer after the diagnosis of Parkinson's disease: a historical cohort study
10.1002/mds.20401 · 2005 · External reference
Nonfatal cancer preceding Parkinson's disease: a case–control study
10.1097/00001648-200203000-00010 · 2002 · External reference
10.1136/jnnp.2009.175463
10.1136/jnnp.2009.175463 · External reference
Malignant melanoma and other types of cancer preceding Parkinson disease
10.1097/01.ede.0000229445.90471.5e · 2006 · External reference
Atypical cancer pattern in patients with Parkinson's disease
10.1038/sj.bjc.6602279 · 2005 · External reference
10.1007/s10552-009-9497-6
10.1007/s10552-009-9497-6 · External reference
Mortality cancer risk in parkinsonian patients: a population-based study
10.1212/wnl.52.2.395 · 1999 · External reference
Occurrence of different cancers in patients with Parkinson's disease
10.1136/bmj.310.6993.1500 · 1995 · External reference
Unresolved reference
1962 · External reference
The relationship between cancer and Alzheimer's disease
10.1111/j.1532-5415.1991.tb02713.x · 1991 · External reference
Prevalence and risks of dementia in the Japanese population: RERF's adult health study Hiroshima subjects. Radiation Effects Research Foundation
10.1111/j.1532-5415.1999.tb04577.x · 1999 · External reference
Alzheimer disease and cancer
10.1212/01.wnl.0000152889.94785.51 · 2005 · External reference
Cancer linked to Alzheimer disease but not vascular dementia
10.1212/wnl.0b013e3181c91873 · 2010 · External reference
Unresolved reference
External reference
Unresolved reference
2011 · External reference
Smoking as a risk factor for dementia and cognitive decline: a meta-analysis of prospective studies
10.1093/aje/kwm116 · 2007 · External reference
A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease
10.1002/ana.10277 · 2002 · External reference
Update in the epidemiology of Parkinson's disease
10.1097/wco.0b013e3283050461 · 2008 · External reference
10.1007/s10654-011-9581-6
10.1007/s10654-011-9581-6 · External reference
10.1016/s1568-1637(02)00005-3 · 2002 · Admitted local publication
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
10.1126/science.8346443 · 1993 · External reference
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
10.1073/pnas.90.5.1977 · 1993 · External reference
Apolipoprotein E epsilon 4 allele and the lifetime risk of Alzheimer's disease. What physicians know, and what they should know
10.1001/archneur.1995.00540350068018 · 1995 · External reference
Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study
10.1001/archneur.55.7.964 · 1998 · External reference
Influences of apolipoprotein E polymorphism on the risk for breast cancer and HER2/neu status in Taiwan
10.1007/s10549-004-4656-7 · 2005 · External reference
Apolipoprotein E and the risk of breast cancer in African-American and non-Hispanic white women. A review
10.1159/000077433 · 2004 · External reference
Unresolved reference
External reference
Apolipoprotein E polymorphism and breast carcinoma: correlation with cell proliferation indices and clinical outcome
10.1023/a:1006464409137 · 2000 · External reference
Apolipoprotein E genetic polymorphism, serum lipoproteins, and breast cancer risk
10.1002/(sici)1098-2744(200001)27:1<2::aid-mc2>3.0.co;2-w · 2000 · External reference
Apolipoprotein E phenotype, cholesterol and breast and prostate cancer
10.1136/jech.54.12.938 · 2000 · External reference
Insulin-like growth factor-I (IGF-I) immunoreactivity in the Alzheimer's disease temporal cortex and hippocampus
10.1016/s0169-328x(97)00192-7 · 1997 · External reference
Mitotic signaling by beta-amyloid causes neuronal death
10.1096/fasebj.13.15.2225 · 1999 · External reference
Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease
10.1523/jneurosci.13-06-02540.1993 · 1993 · External reference
beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes
10.1523/jneurosci.18-12-04451.1998 · 1998 · External reference
Characterization of cytokine production, screening of lymphocyte subset patterns and in vitro apoptosis in healthy and Alzheimer's Disease (AD) individuals
10.1016/s0165-5728(99)00046-6 · 1999 · External reference
Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology
10.1016/s0197-4580(01)00282-2 · 2002 · External reference
Oxidative damage is the earliest event in Alzheimer disease
10.1093/jnen/60.8.759 · 2001 · External reference
Alzheimer disease, the two-hit hypothesis: an update
10.1016/j.bbadis.2006.10.014 · 2007 · External reference
When parsimony backfires: neglecting DNA repair may doom neurons in Alzheimer's disease
10.1002/bies.10227 · 2003 · External reference
Why do neurons enter the cell cycle?
10.4161/cc.3.6.901 · 2004 · External reference
Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease
10.1002/1097-4547(20000715)61:2<128::aid-jnr2>3.3.co;2-8 · 2000 · External reference
Increased chromosome instability dramatically disrupts neural genome integrity and mediates cerebellar degeneration in the ataxia–telangiectasia brain
10.1093/hmg/ddp207 · 2009 · External reference
Aneuploidy in the normal, Alzheimer's disease and ataxia–telangiectasia brain: differential expression and pathological meaning
10.1016/j.nbd.2009.01.003 · 2009 · External reference
10.1091/mbc.e09-10-0850
10.1091/mbc.e09-10-0850 · External reference
The cell cycle hypothesis of Alzheimer's disease: suggestions for drug development
10.1016/j.bbadis.2006.12.004 · 2007 · External reference
10.1523/jneurosci.0710-11.2011
10.1523/jneurosci.0710-11.2011 · External reference
Putting the ‘HAT’ back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions
10.1517/13543780902810345 · 2009 · External reference
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
10.1038/ng1362 · 2004 · External reference
10.1517/14728222.2010.510134
10.1517/14728222.2010.510134 · External reference
10.1016/j.neubiorev.2010.09.006
10.1016/j.neubiorev.2010.09.006 · External reference
Patterns of dementia diagnosis in surveillance, epidemiology, and end results breast cancer survivors who use chemotherapy
10.1111/j.1532-5415.2008.01848.x · 2008 · External reference
Risk of dementia in older breast cancer survivors: a population-based cohort study of the association with adjuvant chemotherapy
10.1111/j.1532-5415.2008.02130.x · 2009 · External reference
Resveratrol improves health and survival of mice on a high-calorie diet
10.1038/nature05354 · 2006 · External reference
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
10.1074/jbc.m602909200 · 2006 · External reference
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
10.1038/sj.emboj.7601758 · 2007 · External reference
The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth
10.1371/journal.pone.0002020 · 2008 · External reference
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
10.1038/nature06261 · 2007 · External reference
Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases
10.1016/s0896-6273(01)00177-5 · 2001 · External reference
Altered proteasomal function in sporadic Parkinson's disease
10.1006/exnr.2002.8050 · 2003 · External reference
Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease
10.1002/ana.20186 · 2004 · External reference
The proteasome: a novel target for anticancer therapy
10.1007/s12094-006-0176-8 · 2006 · External reference
Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line
10.1016/j.chembiol.2003.08.010 · 2003 · External reference
Parkin gene alterations in hepatocellular carcinoma
10.1002/gcc.20020 · 2004 · External reference
Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27
10.1073/pnas.0931262100 · 2003 · External reference
Silencing of the UCHL1 gene in human colorectal and ovarian cancers
10.1002/ijc.22025 · 2006 · External reference
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
10.1016/s0896-6273(03)00084-9 · 2003 · External reference
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
10.1126/science.1077209 · 2003 · External reference
DJ-1, a novel regulator of the tumor suppressor PTEN
10.1016/j.ccr.2005.02.010 · 2005 · External reference
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
10.1172/jci37617 · 2009 · External reference
Tumours and tremors: how PTEN regulation underlies both
10.1038/sj.bjc.6602994 · 2006 · External reference
Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN
2001 · External reference
Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway
10.1038/sj.onc.1204608 · 2001 · External reference
10.1007/s12079-011-0121-7
10.1007/s12079-011-0121-7 · External reference
Proteasome regulators: activators and inhibitors
10.2174/092986709787581860 · 2009 · External reference
Proteasome activator enhances survival of Huntington's disease neuronal model cells
10.1371/journal.pone.0000238 · 2007 · External reference
10.1002/syn.20719
10.1002/syn.20719 · External reference
The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts
10.1089/rej.2006.0513 · 2007 · External reference
Algae extract-mediated stimulation and protection of proteasome activity within human keratinocytes exposed to UVA and UVB irradiation
10.1089/ars.2006.8.136 · 2006 · External reference
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway
10.1128/mcb.23.23.8786-8794.2003 · 2003 · External reference
Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides
10.1074/jbc.m508246200 · 2005 · External reference
Trade-off between cancer and aging: what role do other diseases play? Evidence from experimental and human population studies
10.1016/j.mad.2008.03.006 · 2009 · External reference
Cancer and ageing: rival demons?
10.1038/nrc1073 · 2003 · External reference
Surfing the p53 network
10.1038/35042675 · 2000 · External reference
Variation in the human TP53 gene affects old age survival and cancer mortality
10.1016/j.exger.2004.10.001 · 2005 · External reference
To die or grow: Parkinson's disease and cancer
10.1016/j.tins.2005.05.002 · 2005 · External reference
A common biological mechanism in cancer and Alzheimer's disease?
10.2174/156720509788486608 · 2009 · External reference
A human peptidyl–prolyl isomerase essential for regulation of mitosis
10.1038/380544a0 · 1996 · External reference
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism
10.1126/science.278.5345.1957 · 1997 · External reference
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease
10.1038/nrm2261 · 2007 · External reference
Pinning down cell signaling, cancer and Alzheimer's disease
10.1016/j.tibs.2004.02.002 · 2004 · External reference
Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes
10.1073/pnas.032404099 · 2002 · External reference
Pin1 is an E2F target gene essential for the Neu/Ras-induced transformation of mammary epithelial cells
10.1128/mcb.22.15.5281-5295.2002 · 2002 · External reference
Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
10.1038/ncb0901-793 · 2001 · External reference
Pin1 is overexpressed in breast cancer and potentiates the transcriptional activity of phosphorylated c-Jun towards the cyclin D1 gene
10.1093/emboj/20.13.3459 · 2001 · External reference
Prevalent overexpression of prolyl isomerase Pin1 in human cancers
10.1016/s0002-9440(10)63731-5 · 2004 · External reference
Pin1 is a novel prognostic marker in prostate cancer
2003 · External reference
Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis
2000 · External reference
Modeling breast cancer in vivo and ex vivo reveals an essential role of Pin1 in tumorigenesis
10.1038/sj.emboj.7600323 · 2004 · External reference
Ablation of a peptidyl prolyl isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch1
10.1038/sj.onc.1210153 · 2007 · External reference
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
10.1038/nature01832 · 2003 · External reference
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
10.1038/21650 · 1999 · External reference
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production
10.1038/nature04543 · 2006 · External reference
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
10.1016/s1097-2765(05)00083-3 · 2000 · External reference
Pin1 in Alzheimer's disease
10.1111/j.1471-4159.2006.03995.x · 2006 · External reference
Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease
10.1016/j.nbd.2005.11.002 · 2006 · External reference
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: a redox proteomics analysis
10.1016/j.neurobiolaging.2005.05.005 · 2006 · External reference