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References from A cell death-independent role for MLKL in TGF-β receptor recycling in Marfan syndrome. Local targets link to admitted publications; unresolved targets remain external evidence.
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FBN1 Mutations in Patients With Descending Thoracic Aortic Dissections
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Progressive Microstructural Deterioration Dictates Evolving Biomechanical Dysfunction in the Marfan Aorta
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Type I and type V procollagen triple helix uses different subsets of the molecular ensemble for lysine posttranslational modifications in the rER
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Loss of MLKL impairs abdominal aortic aneurysm development by attenuating smooth muscle cell necroptosis
10.1038/s41419-026-08427-4 · 2026 · External reference
Myeloperoxidase aggravates thoracic aortic aneurysm formation in Marfan disease
10.1093/cvr/cvaf248 · 2026 · External reference
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MLKL activity requires a splicing-regulated, druggable intramolecular interaction
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The role of collagen and collagen I/III ratio in pathological conditions: insights into molecular mechanisms and therapeutic approaches
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Substitution of murine type I collagen A1 3-hydroxylation site alters matrix structure but does not recapitulate osteogenesis imperfecta bone dysplasia
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Beyond Collagen Biosynthesis: Prolyl-3-Hydroxylase 1 Controls Extracellular Matrix Dynamics by Suppressing Transforming Growth Factor β2
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10.1186/2045-3701-2-9 · Admitted local publication
MLKL as an emerging machinery for modulating organelle dynamics: regulatory mechanisms, pathophysiological significance, and targeted therapeutics
10.3389/fphar.2025.1512968 · 2025 · External reference
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10.3390/ijerph18083874 · External reference
Flotillin-mediated endocytosis and ALIX–syntenin-1– mediated exocytosis protect the cell membrane from damage caused by necroptosis
10.1126/scisignal.aaw3423 · 2019 · External reference
MLKL/retromer axis controls PD-L1 recycling to compromise antitumor immunity during VCP inhibition–induced necroptosis
10.1073/pnas.2518675122 · 2025 · External reference
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Nitro-oleic acid reduces thoracic aortic aneurysm progression in a mouse model of Marfan syndrome
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Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells
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