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Guillem Prats-Ejarque
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Eosinophil granule proteins: form and function
10.1074/jbc.r113.546218 · 2014
Distinctive cationic proteins of the human eosinophil granule: major basic protein, eosinophil cationic protein, and eosinophil-derived neurotoxin
10.4049/jimmunol.131.6.2977 · 1983
Comparative toxicity of purified human eosinophil granule cationic proteins for schistosomula of Schistosoma mansoni
10.4269/ajtmh.1985.34.735 · 1985
Polymorphisms in the RNASE3 gene are associated with susceptibility to cerebral malaria in Ghanaian children
10.1371/journal.pone.0029465 · 2011
Amino acid sequence of an anti-tumor protein from Rana pipiens oocytes and early embryos. Homology to pancreatic ribonucleases
10.1016/s0021-9258(18)52427-3 · 1991
Ribonucleases as potential modalities in anticancer therapy
10.1016/j.ejphar.2009.06.067 · 2009
A ribonuclease inhibitor resistant dimer of human pancreatic ribonuclease displays specific antitumor activity
10.1016/j.ijbiomac.2017.10.067 · 2018
OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug
10.1073/pnas.1815071116 · 2019
Mammalian antimicrobial proteins and peptides: overview on the RNase A superfamily members involved in innate host defence
10.1039/b617527a · 2007
Role of the N terminus in RNase a homologues: differences in catalytic activity, ribonuclease inhibitor interaction and cytotoxicity
10.1006/jmbi.1996.0218 · 1996
The antipathogen activities of eosinophil cationic protein
10.2174/138920108784567353 · 2008
Structural determinants of the eosinophil cationic protein antimicrobial activity
10.1515/hsz-2012-0160 · 2012
Both aromatic and cationic residues contribute to the membrane-lytic and bactericidal activity of eosinophil cationic protein
10.1021/bi0273011 · 2003
Rnase L triggers autophagy in response to viral infections
10.1128/jvi.00270-12 · 2012
MCPIP1 negatively regulate cellular antiviral innate immune responses through DUB and disruption of TRAF3-TBK1-IKKε complex
10.1016/j.bbrc.2018.06.083 · 2018
The ribonuclease a superfamily of mammals and birds: identifying new members and tracing evolutionary histories
10.1016/j.ygeno.2004.10.008 · 2005
Bovine pancreatic ribonuclease: fifty years of the first enzymatic reaction mechanism
10.1021/bi201075b · 2011
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins
10.3390/ijms23031647 · 2022
ISG20, an actor of the innate immune response
10.1016/j.biochi.2007.03.006 · 2007
ISG20: an enigmatic antiviral RNase targeting multiple viruses
10.1002/2211-5463.13382 · 2022
Ribonuclease Inhibitor: structure and function
10.1016/s0079-6603(05)80009-1 · 2005
Genetic variants of RNASE3 (ECP) and susceptibility to severe malaria in Senegalese population
10.1186/s12936-018-2205-9 · 2018
Recombinant human eosinophil-derived neurotoxin/RNase 2 functions as an effective antiviral agent against respiratory syncytial virus
10.1086/515322 · 1998
The flexibility of a distant loop modulates active site motion and product release in ribonuclease A
10.1021/bi900830g · 2009
Antimicrobial synergy of a ribonuclease and a peptide secreted by human cells
10.1021/acsinfecdis.0c00594 · 2020
Influenza virus inactivated by artificial ribonucleases as a prospective killed virus vaccine
10.1016/j.vaccine.2012.02.051 · 2012
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells
10.1016/j.bbamcr.2014.01.025 · 2014
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner
10.1016/j.bbamcr.2014.12.016 · 2015
Polyamine derivatives as selective RNaseA mimics
10.1093/nar/gkh157 · 2004
Perturbation of the conformational dynamics of an active-site loop alters enzyme activity
10.1016/j.str.2015.10.011 · 2015
Leukotriene B 4 -mediated release of antimicrobial peptides against cytomegalovirus Is BLT1 dependent
10.1089/vim.2006.0099 · 2007
Angiogenin promotes hematopoietic regeneration by dichotomously regulating quiescence of stem and progenitor cells
10.1016/j.cell.2016.06.042 · 2016
Viral genome cleavage with artificial ribonucleases: a new method to inactivate RNA-containing viruses
10.1134/s1607672909040140 · 2009
The expansion and functional diversification of the mammalian ribonuclease a superfamily epitomizes the efficiency of multigene families at generating biological novelty
10.1093/gbe/evt161 · 2013
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs
10.3389/fimmu.2019.02626 · 2019
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme
10.1016/j.ijbiomac.2021.09.095 · 2021
The mammalian secreted RNases: mechanisms of action in host defence
10.1177/1753425912446955 · 2013
The role of antimicrobial peptides in animal defenses
10.1073/pnas.97.16.8856 · 2000
Rnase activity of a DNA minor groove binder with a minimalist catalytic motif from RNase A
10.1006/bbrc.2001.4503 · 2001
A human ribonuclease variant and ERK-pathway inhibitors exhibit highly synergistic toxicity for cancer cells
10.1158/1535-7163.mct-18-0724 · 2018
RNA drugs and RNA targets for small molecules: principles, progress, and challenges
10.1124/pr.120.019554 · doi-reference
Plexin-B2 mediates physiologic and pathologic functions of angiogenin
10.1016/j.cell.2017.10.005 · doi-reference
Eosinophil-derived neurotoxin (EDN), an antimicrobial protein with chemotactic activities for dendritic cells
10.1182/blood-2003-01-0151 · doi-reference
Expression of human ACE2 N-terminal domain, part of the receptor for SARS-CoV-2, in fusion with maltose-binding protein, E. coli ribonuclease I and human RNase A
10.3389/fmicb.2021.660149 · doi-reference
ANG promotes proliferation and invasion of the cell of lung squamous carcinoma by Directly Up-regulating HMGA2
10.7150/jca.14440 · doi-reference
A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity
10.1016/s0021-9258(18)82252-9 · doi-reference
Killing of Plasmodium falciparum by eosinophil secretory products
10.1128/iai.55.4.877-881.1987 · doi-reference
Angiogenin/Ribonuclease 5 Is an EGFR ligand and a serum biomarker for erlotinib sensitivity in pancreatic cancer
10.1016/j.ccell.2018.02.012 · doi-reference
Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus
10.1042/bj20130123 · doi-reference
Exploring new biological functions of amyloids: bacteria cell agglutination mediated by host protein aggregation
10.1371/journal.ppat.1003005 · doi-reference
Refining the eosinophil cationic protein antibacterial pharmacophore by rational structure minimization
10.1021/jm200701g · doi-reference
Connecting peptide physicochemical and antimicrobial properties by a rational prediction model
10.1371/journal.pone.0016968 · doi-reference
Eosinophil cationic protein aggregation: identification of an N-terminus amyloid prone region
10.1021/bm100334u · doi-reference
Comparison of the membrane interaction mechanism of two antimicrobial RNases: RNase 3/ECP and RNase 7
10.1016/j.bbamem.2009.01.013 · doi-reference
Bactericidal and membrane disruption activities of the eosinophil cationic protein are largely retained in an N-terminal fragment
10.1042/bj20082330 · doi-reference
Bactericidal activity engineered on human pancreatic ribonuclease and onconase
10.1021/mp8001914 · doi-reference
Eosinophil cationic protein high-affinity binding to bacteria-wall lipopolysaccharides and peptidoglycans
10.1021/bi702065b · doi-reference
Topography studies on the membrane interaction mechanism of the eosinophil cationic protein
10.1021/bi061190e · doi-reference
Serum levels of eosinophil cationic protein, eosinophil-derived neurotoxin and myeloperoxidase in infections with filariea and schistosomes
10.1016/s0001-706x(96)00038-1 · doi-reference
Knockout of the ribonuclease inhibitor gene leaves human cells vulnerable to secretory ribonucleases
10.1021/acs.biochem.6b01003 · doi-reference
Design, RNA cleavage and antiviral activity of new artificial ribonucleases derived from mono-, di- and tripeptides connected by linkers of different hydrophobicity
10.1016/j.bmc.2016.02.007 · doi-reference
MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation
10.1016/j.molcel.2011.09.012 · doi-reference
Structure-function relationships in human ribonucleases: main distinctive features of the major RNase types
10.1016/s0014-5793(97)00086-0 · doi-reference
Human pancreatic-type and nonpancreatic-type ribonucleases: a direct side-by-side comparison of their catalytic properties
10.1006/abbi.1994.1318 · doi-reference
The eight human “canonical” ribonucleases: molecular diversity, catalytic properties, and special biological actions of the enzyme proteins
10.1016/j.febslet.2010.04.018 · doi-reference
Enzymatic and structural characterisation of amphinase, a novel cytotoxic ribonuclease from Rana pipiens oocytes
10.1016/j.jmb.2007.04.071 · doi-reference
Role of unique basic residues in cytotoxic, antibacterial and antiparasitic activities of human eosinophil cationic protein
10.1515/bc.2011.037 · doi-reference
Viral encounters with 2′,5′-oligoadenylate synthetase and RNase L during the interferon antiviral response
10.1128/jvi.01471-07 · doi-reference
RNase L induces autophagy via c-Jun N-terminal kinase and double-stranded RNA-dependent protein kinase signaling pathways
10.1074/jbc.m112.399964 · doi-reference
HIV and ribozymes
10.1007/978-1-4939-2432-5_5 · doi-reference
Rationally modified antimicrobial peptides from the N-terminal domain of human RNase 3 show exceptional serum stability
10.1021/acs.jmedchem.1c00795 · doi-reference
Insight into the antifungal mechanism of action of human RNase N-terminus derived peptides
10.3390/ijms20184558 · doi-reference
Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity
10.2174/138920108784567344 · doi-reference
Ribonuclease is partly responsible for the HIV-1 inhibitory effect activated by HLA alloantigen recognition
10.1097/00002030-200303070-00002 · doi-reference
Eosinophils: changing perspectives in health and disease
10.1038/nri3341 · doi-reference
Eosinophil-derived neurotoxin (EDN/RNase 2) and the mouse eosinophil-associated RNases (mEars): expanding roles in promoting host defense
10.3390/ijms160715442 · doi-reference
Eosinophil-derived neurotoxin/RNase 2: connecting the past, the present and the future
10.2174/138920108784567236 · doi-reference
RNase A ribonucleases and host defense: an evolving story
10.1189/jlb.1107725 · doi-reference
The eosinophil ribonucleases
10.1007/s000180050208 · doi-reference
Recombinant human eosinophil cationic protein: ribonuclease activity is not essential for cytotoxicity
10.1074/jbc.270.14.7876 · doi-reference