Abstract
No public abstract is available from the verified source records.
Minhal Abidi, Sana Iram, Jamal-E -Fatima, Hamda Khan, Shaheda Perween, Safia Habib, Moinuddin
Abstract
Authors
Institutions
No local reference links have been materialized yet.
No local citing links have been materialized yet.
Protein aggregation diseases: pathogenicity and therapeutic perspectives
10.1038/nrd3050 · 2010
Protein misfolding and dysregulated protein homeostasis in autoinflammatory diseases and beyond
10.1007/s00281-015-0496-2 · 2015
Unresolved referenced work
2013
“STRESSED OUT”: the role of FUS and TDP-43 in amyotrophic lateral sclerosis
10.1016/j.biocel.2020.105821 · 2020
Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing
10.1038/s41580-020-00326-6 · 2021
Is there more to aging than mitochondrial DNA and reactive oxygen species?
10.1111/j.1742-4658.2009.07269.x · 2009
Structure and aggregation mechanisms in amyloids
10.3390/molecules25051195 · 2020
Mitochondrial dysfunction and oxidative stress in Alzheimer’s disease, and Parkinson’s disease, Huntington’s disease and Amyotrophic Lateral Sclerosis -An updated review
10.1016/j.mito.2023.05.007 · 2023
Amyloid solutions: lecanemab, gantenerumab, and donanemab in the treatment of Alzheimer’s disease
2025
Provenance
crossref
Confidence 100%
openalex
Confidence 95%
datacite
Confidence 0%
Protein aggregation and neurodegenerative disease: Structural outlook for the novel therapeutics
10.1002/prot.26561 · 2025
Glycation and a spark of ALEs (advanced lipoxidation end products) – igniting RAGE/diaphanous-1 and cardiometabolic disease
10.3389/fcvm.2022.937071 · 2022
Unresolved referenced work
Kept as external metadata until matched
Modulators of amyloid protein aggregation and toxicity: EGCG and CLR01
10.2478/s13380-013-0137-y · 2013
Molecular and biological hallmarks of ageing
10.1002/bjs.10053 · 2016
Mass spectrometry for neurobiomarker discovery: the relevance of post-translational modifications
10.3390/cells11081279 · 2022
Cognitive synaptopathy: synaptic and dendritic spine dysfunction in age-related cognitive disorders
10.3389/fnagi.2024.1476909 · 2024
Probing protein aggregation through spectroscopic insights and multimodal approaches: a comprehensive review for counteracting neurodegenerative disorders
10.1016/j.heliyon.2024.e27949 · 2024
Interplay between autophagy and the ubiquitin-proteasome system and its role in the pathogenesis of age-related macular degeneration
10.3390/ijms20010210 · 2019
Cryo-EM structural features of glutamate receptors involved in synaptic neurotransmission or brain pathology
2024
Unresolved referenced work
Kept as external metadata until matched
Redox events in interleukin-1 signaling
10.1016/j.abb.2003.12.008 · 2004
Structural insights into the catalysis and regulation of E3 ubiquitin ligases
10.1038/nrm.2016.91 · 2016
The shock of aging: molecular chaperones and the heat shock response in longevity and aging - a mini-review
10.1159/000225957 · 2009
Protein aggregation landscape in neurodegenerative diseases: clinical relevance and future applications
10.3390/ijms22116016 · 2021
Unresolved referenced work
2021
Diverse functions of Tim50, a component of the mitochondrial inner membrane protein translocase
10.3390/ijms22157779 · 2021
Tau inclusions in Alzheimer’s, chronic traumatic encephalopathy and Pick’s disease. A speculation on how differences in backbone polarization underlie divergent pathways of tau aggregation
2019
10.1101/2023.02.09.527812
10.1101/2023.02.09.527812
10.2174/187152710791012053
10.2174/187152710791012053
The cryo-EM effect: structural biology of neurodegenerative disease aggregates
10.1093/jnen/nlab039 · 2021
Tafamidis for autonomic neuropathy in hereditary transthyretin (ATTR) amyloidosis: a review
10.1007/s10286-019-00625-9 · 2019
Dynamic protein interaction networks and new structural paradigms in signaling
10.1021/acs.chemrev.5b00548 · 2016
Role of protein misfolding and proteostasis deficiency in protein misfolding diseases and aging
10.1155/2013/638083 · 2013
Unresolved referenced work
2022
Unresolved referenced work
Kept as external metadata until matched
The cell biology of aging
10.1091/mbc.e14-06-1084 · 2015
Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS
10.1089/ars.2006.8.163 · 2006
Mass spectrometry-based detection and assignment of protein posttranslational modifications
10.1021/cb500904b · 2015
The H+-ATPase (V-ATPase): from proton pump to signaling complex in health and disease
10.1152/ajpcell.00442.2020 · 2021
Ageing-oxidative stress, PTMs and disease
10.1016/j.mam.2022.101099 · 2022
Lessons from the discovery of mitochondrial fragmentation (fission): a review and update
10.3390/cells8020175 · doi-reference
The roles of mitochondrial dysfunction and reactive oxygen species in aging and senescence
10.2174/1566524021666210218112616 · doi-reference
Recent studies of atomic-resolution structures of tau protein and structure-based inhibitors
10.15302/j-qb-021-0271 · doi-reference
Protein posttranslational modifications in health and diseases: functions, regulatory mechanisms, and therapeutic implications
10.1002/mco2.261 · doi-reference
Novel tau filament fold in corticobasal degeneration
10.1038/s41586-020-2043-0 · doi-reference
Current technologies unraveling the significance of post-translational modifications (PTMs) as crucial players in neurodegeneration
10.3390/biom14010118 · doi-reference
Structural evaluations of tau protein conformation: methodologies and approaches
10.1139/bcb-2016-0227 · doi-reference
Studying membrane modulation mechanisms by electron cryo-tomography
10.1016/j.sbi.2022.102464 · doi-reference
Mechanistic study of optic atrophy 1 in ischemia-reperfusion disease
10.1007/s00109-022-02271-7 · doi-reference
Reaction mechanism of cytochrome c oxidase
10.1021/cr500266a · doi-reference
Multimodal imaging markers of cognitive resilience and molecular mechanisms of brain resilience in Alzheimer’s disease
10.31083/jin26584 · doi-reference
Cryo-EM structures of amyloid-b 42 filaments from human brains
10.1126/science.abm7285 · doi-reference
Self-assembling peptide biomaterials: Insights from spontaneous and enhanced sampling molecular dynamics simulations
10.1063/5.0142302 · doi-reference
Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging
10.1177/153537020222700901 · doi-reference
Activation of NLRP3-Caspase-1 pathway contributes to age-related impairments in cognitive function and synaptic plasticity
10.1016/j.neuint.2021.105220 · doi-reference
The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling
10.1083/jcb.128.4.637 · doi-reference
On the hypes and falls in neuroprotection: targeting the NMDA receptor
10.1177/1073858406296259 · doi-reference
Precision medicine in rare diseases
10.3390/diseases8040042 · doi-reference
Chaperoning the cancer: the proteostatic functions of the heat shock proteins in cancer
10.2174/1574892811666161102125252 · doi-reference
An overview on glycation: molecular mechanisms, impact on proteins, pathogenesis, and inhibition
10.1007/s12551-024-01188-4 · doi-reference
The evolving role of solid state nuclear magnetic resonance methods in studies of amyloid fibrils
10.1016/j.sbi.2025.103043 · doi-reference
Caspase involvement in autophagy
10.1038/cdd.2017.43 · doi-reference
Multisteric regulation by structural disorder in modular signaling proteins: an extension of the concept of allostery
10.1021/cr4005082 · doi-reference
Decoding neurodegeneration: a review of molecular mechanisms and therapeutic advances in Alzheimer’s, Parkinson’s, and ALS
10.3390/ijms252312613 · doi-reference
Characteristic hallmarks of aging and the impact on carcinogenesis
10.2174/1568009622666220816120353 · doi-reference
Autophagy, organelles and ageing
10.1002/path.2094 · doi-reference
Differentiation and characterization of excitatory and inhibitory synapses by cryo-electron tomography and correlative microscopy
10.1523/jneurosci.1548-17.2017 · doi-reference
Conformational heterogeneity and probability distributions from single-particle cryo-electron microscopy
10.1016/j.sbi.2023.102626 · doi-reference
Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer’s disease
10.1111/pin.12520 · doi-reference
Protein misfolding in neurodegenerative diseases: implications and strategies
10.1186/s40035-017-0077-5 · doi-reference
Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism
10.1016/j.str.2013.09.023 · doi-reference
Synaptotagmins: C2-domain proteins that regulate membrane traffic
10.1016/s0896-6273(00)80171-3 · doi-reference
The mitochondrial basis of aging and age-related disorders
10.3390/genes8120398 · doi-reference
Regulation of PINK1-Parkin-mediated mitophagy
10.4161/auto.7.3.14348 · doi-reference
Trial of solanezumab in preclinical Alzheimer’s disease
10.1056/nejmoa2305032 · doi-reference
Proteostasis disturbances and inflammation in neurodegenerative diseases
10.3390/cells9102183 · doi-reference
Understanding the role of protein glycation in the amyloid aggregation process
10.3390/ijms22126609 · doi-reference
A glimpse of structural biology through X-ray crystallography
10.1016/j.cell.2014.10.051 · doi-reference
Ubiquitination and selective autophagy
10.1038/cdd.2012.72 · doi-reference
Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes
10.1038/s41593-019-0423-2 · doi-reference