Challenges in the diagnosis of Parkinson's disease
10.1016/s1474-4422(21)00030-2 · 2021
Alzheimer’s disease
10.1016/s0140-6736(15)01124-1 · 2016
Neuroprotective effects of gypenosides: a review on preclinical studies in neuropsychiatric disorders
10.1016/j.ejphar.2024.176766 · 2024
Catha edulis and Datura stramonium mitigate oxidative stress, mitochondrial dysfunction, and cell death in an SH-SY5Y model of Parkinson's disease
10.1016/j.jep.2026.121223 · 2026
Neurotoxicity study of ethyl acetate extract of Zanthoxylum armatum DC
10.1016/j.jep.2023.117321 · 2024
Neuroprotective and antioxidant effects of fermented spent coffee ground fractions against Alzheimer's-related oxysterol 27-hydroxycholesterol in SH-SY5Y neuronal cells
10.1016/j.foodchem.2026.149435 · 2026
Neuroprotective effects of pepsin-hydrolyzed ovotransferrin on H2O2-induced oxidative damage in SH-SY5Y neuronal cells
10.1016/j.bioorg.2026.109613 · 2026
Wnt3a protects SH-SY5Y cells against 6-hydroxydopamine toxicity by restoration of mitochondria function
10.1186/s40035-015-0033-1 · 2015
NRF2: master regulator of cellular homeostasis and therapeutic vulnerability in cancer
10.1016/j.redox.2026.104050 · 2026
Nrf2–Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species
10.1016/j.advenzreg.2006.01.007 · 2006
New sweet-tasting gypenosides from “Jiaogulan” (Gynostemma pentaphyllum) and their interactions with the homology model of sweet taste receptors
10.1021/acs.jafc.4c03566 · 2024
Sensory-guided isolation and identification of new sweet-tasting dammarane-type saponins from Jiaogulan (Gynostemma pentaphyllum) herbal tea
10.1016/j.foodchem.2022.132981 · 2022
Further new gypenosides from jiaogulan (Gynostemma pentaphyllum)
10.1021/acs.jafc.7b01477 · 2017
Saponins derived from Gynostemma pentaphyllum regulate triglyceride and cholesterol metabolism and the mechanisms: a review
10.1016/j.jep.2023.117186 · 2024
Gynostemma pentaphyllum polysaccharides alleviate ulcerative colitis in mice via the Nrf2/ROS/NLRP3 axis and modulation of the gut microbiota
10.1016/j.jep.2026.121373 · 2026
Metabolomics and molecular docking-directed anti-obesity study of the ethanol extract from Gynostemma pentaphyllum (Thunb.) Makino
10.1016/j.jep.2024.118577 · 2024
New dammarane-type glycosides from Gynostemma pentaphyllum and their lipid-lowering activity
10.1016/j.bioorg.2021.104843 · 2021
Gypenoside L inhibits oral squamous cell carcinoma progression by targeting the AKT signaling pathway
10.1016/j.bioorg.2025.109303 · 2026
Identification and mechanism of hepatoprotective saponins and endogenous metabolites in the sweet variant of Gynostemma pentaphyllum
10.1016/j.bioorg.2025.108996 · 2025
Gypenoside TN-2 ameliorates scopolamine-induced learning deficit in mice
10.1016/j.jep.2011.02.002 · 2011
Neuroprotective effects of Gynostemma pentaphyllum (Jiaogulan): mechanisms, active compounds, and therapeutic potential
10.1016/j.prmcm.2026.100760 · 2026
Triterpenoids from the genus Gynostemma: chemistry and pharmacological activities
2021
Diploid chromosome-level reference genome and population genomic analyses provide insights into Gypenoside biosynthesis and demographic evolution of Gynostemma pentaphyllum (Cucurbitaceae)
10.1093/hr/uhac231 · 2023
Untargeted qualitative and targeted quantitative analysis of saponins reveal differential chemotypes of Gynostemma pentaphyllum and G. longipes from different geographical origins
10.1016/j.foodchem.2024.142412 · 2025
Correlation analysis of taste phenotype and Gynostemma pentaphyllum saponins using computer virtual screening and UPLC-(HR)MS/MS metabolomics
10.1016/j.foodchem.2024.142050 · 2025
Untargeted qualitative and targeted quantitative analysis of saponins reveal differential chemotypes of Gynostemma pentaphyllum and G. longipes from different geographical origins
10.1016/j.foodchem.2024.142412 · 2025
Population genetic structure, migration, and polyploidy origin of a medicinal species Gynostemma pentaphyllum (Cucurbitaceae)
10.1002/ece3.5618 · 2019
Synthesis, characterization, crystal structure and evaluation of four carbazole-coumarin hybrids as multifunctional agents for the treatment of Alzheimer’s disease
10.1016/j.molstruc.2020.127897 · 2020
Neuroprotective and antioxidant properties of Polygala virgata fractions in a 6-hydroxydopamine-induced neurotoxicity model
10.1016/j.jep.2026.121222 · 2026
Icariin exerts an antidepressant effect in an unpredictable chronic mild stress model of depression in rats and is associated with the regulation of hippocampal neuroinflammation
10.1016/j.neuroscience.2015.02.053 · 2015
Six new triterpenoid glycosides from Gynostemma pentaphyllum
10.1002/hlca.200900100 · 2009
A novel kaempferol triglycoside from flower buds of Panax quinquefolium
10.1007/s10600-010-9500-1 · 2009
A new phloroglucinol diglycoside derivative from Hypericum japonicum Thunb
10.3390/molecules13112796 · 2008
Inhibitory activity of isorhamnetin from Persicaria thunbergii on farnesyl protein transferase
10.1007/bf02977709 · 2005
Flavonoid glycosides from cuban Erythroxylum species
10.1016/j.bse.2006.01.003 · 2006
The flavonoids of Phragmites australis flowers
10.1016/s0031-9422(00)83831-5 · 1980
Iridoids, flavonoids and monoterpene glycosides from Galium verum subsp. verum
2006
Emerging of a new neuroprotective isoflavonoid with potent Keap1/Nrf2/ARE pathway activation and AChE inhibition
10.1016/j.bioorg.2025.109336 · 2026
Gypenosides protect retinal pigment epithelium cells from oxidative stress
10.1016/j.fct.2017.12.037 · 2018
Multi-target drug design in Alzheimer’s disease treatment: emerging technologies, advantages, challenges, and limitations
10.1002/prp2.70131 · 2025
