High light promotes salicylic acid–dependent diterpenoid lactone biosynthesis in Andrographis paniculate
10.1016/j.ncrops.2025.100094 · doi-reference
Distributing a metabolic pathway among a microbial consortium enhances production of natural products
10.1038/nbt.3095 · doi-reference
Engineering cyanobacteria as a new platform for producing taxol precursors directly from carbon dioxide
10.1186/s13068-024-02555-9 · doi-reference
Parameter optimization of ultrasonic-microwave synergistic extraction of taxanes from Taxus cuspidata needles
10.3390/molecules28237746 · doi-reference
Oxetane ring formation in Taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme
10.1021/jacs.3c10864 · doi-reference
Synthetic biology identifies the minimal gene set required for paclitaxel biosynthesis in a plant chassis
10.1016/j.molp.2023.10.016 · doi-reference
Computational redesign of taxane-10β-hydroxylase for de novo biosynthesis of a key paclitaxel intermediate
10.1007/s00253-023-12784-x · doi-reference
Two jasmonate-responsive factors, TcERF12 and TcERF15, respectively act as repressor and activator of tasy gene of taxol biosynthesis in Taxus chinensis
10.1007/s11103-015-0382-2 · doi-reference
Tissue-specific study across the stem of Taxus media identifies a phloem-specific TmMYB3 involved in the transcriptional regulation of paclitaxel biosynthesis
10.1111/tpj.14710 · doi-reference
Role of an endodermis-specific miR858b-MYB1L module in the regulation of Taxol biosynthesis in Taxus mairei
10.1111/tpj.70135 · doi-reference
miR5298b regulated taxol biosynthesis by acting on TcNPR3, resulting in an alleviation of the strong inhibition of the TcNPR3-TcTGA6 complex in Taxus chinensis
10.1016/j.ijbiomac.2023.125909 · doi-reference
Comprehensive strategies for paclitaxel production: insights from plant cell culture, endophytic microorganisms, and synthetic biology
10.1093/hr/uhae346 · doi-reference
Biosynthesis of the highly oxygenated tetracyclic core skeleton of Taxol
10.1038/s41467-024-46583-3 · doi-reference
Enhanced C30 carotenoid production in Bacillus subtilis by systematic overexpression of MEP pathway genes
10.1007/s00253-015-6531-3 · doi-reference
Enhancing cross-organelle coordination to advance plant cytochrome P450 functionality in yeast
10.1126/sciadv.ady7184 · doi-reference
Strategies to increase the robustness of microbial cell factories
10.1007/s44307-024-00018-8 · doi-reference
Improving solubility and copy number of taxadiene synthase to enhance the titer of taxadiene in Yarrowia lipolytica
10.1016/j.synbio.2023.04.002 · doi-reference
The Taxus genome provides insights into paclitaxel biosynthesis
10.1038/s41477-021-00963-5 · doi-reference
From Taxus to paclitaxel: Opportunities and challenges for urban agriculture to promote human health
10.1016/j.plaphy.2025.109502 · doi-reference
Enhancing the biosynthesis of taxadien-5α-yl-acetate in Escherichia coli by combinatorial metabolic engineering approaches
10.1186/s40643-024-00762-8 · doi-reference
Machine learning-assisted directed protein evolution with combinatorial libraries
10.1073/pnas.1901979116 · doi-reference
Construction of an Escherichia coli cell factory to synthesize taxadien-5α-ol, the key precursor of anti-cancer drug paclitaxel
10.1186/s40643-022-00569-5 · doi-reference
Improving the expression of taxadiene synthase to enhance the titer of taxadiene in Saccharomyces cerevisiae
10.1039/d4gc03079f · doi-reference
Biomimetic light dilution using side-emitting optical fiber for enhancing the productivity of microalgae reactors
10.1038/s41598-019-45955-w · doi-reference
A cDNA clone for taxadiene synthase, the diterpene cyclase that catalyzes the committed step of taxol biosynthesis
10.1074/jbc.271.16.9201 · doi-reference
Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
10.1021/ja00738a045 · doi-reference
Nature as a remarkable chemist: a personal story of the discovery and development of Taxol
10.1097/cad.0000000000000063 · doi-reference
Natural taxanes: developments since 1828
10.1021/cr100147u · doi-reference
The marine diatom Phaeodactylum tricornutum as a versatile bioproduction chassis: current progress, challenges, and perspectives
10.1016/j.xplc.2025.101519 · doi-reference
Exploring the combinatorial space of complete pathways to chemicals
10.1042/bst20170272 · doi-reference
Facile biosynthesis of taxadiene by a newly constructed Escherichia coli strain fusing enzymes taxadiene synthase and geranylgeranyl pyrophosphate synthase
10.1016/j.procbio.2022.09.005 · doi-reference
Acetylation–deacetylation-driven natural product biosynthesis
10.1002/ceur.202500025 · doi-reference
Optimizing the biosynthesis of oxygenated and acetylated Taxol precursors in Saccharomyces cerevisiae using advanced bioprocessing strategies
10.1002/bit.27569 · doi-reference
Definitive screening accelerates Taxol biosynthetic pathway optimization and scale up in Saccharomyces cerevisiae cell factories
10.1002/biot.202100414 · doi-reference
Cloning, heterologous expression, and characterization of a phenylalanine aminomutase involved in Taxol biosynthesis
10.1074/jbc.m411215200 · doi-reference
Molecular cloning and heterologous expression of the C-13 phenylpropanoid side chain-CoA acyltransferase that functions in Taxol biosynthesis
10.1073/pnas.192463699 · doi-reference
The final acylation step in taxol biosynthesis: cloning of the taxoid C13-side-chain N-benzoyltransferase from Taxus
10.1073/pnas.082115799 · doi-reference
Molecular cloning of a taxa-4(20),11(12)-dien-5alpha-ol-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli
10.1006/abbi.1999.1609 · doi-reference
Network analysis of the MVA and MEP pathways for isoprenoid synthesis
10.1146/annurev-arplant-050312-120116 · doi-reference
Investigation of the methylerythritol 4-phosphate pathway for microbial terpenoid production through metabolic control analysis
10.1186/s12934-019-1235-5 · doi-reference
