Abstract
Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Abstract
Authors
Institutions
No ROR-resolved institution is linked to this work yet.
Provenance
crossref
Confidence 100%
pubmed
Confidence 98%
unpaywall
Confidence 95%
datacite
Confidence 0%
No local reference links have been materialized yet.
No local citing links have been materialized yet.
Medicinal chemistry, pharmacology, and potential therapeutic benefits of cannabinoid CB2 receptor agonists
10.1021/acs.chemrev.5b00411 · 2016
Neurochemical basis of cannabis addiction
10.1016/j.neuroscience.2011.02.035 · 2011
The endocannabinoid system and heart disease: the role of cannabinoid receptor type 2
10.2174/1871529x18666180206161457 · 2018
The CB2 receptor and its role as a regulator of inflammation
10.1007/s00018-016-2300-4 · 2016
Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain
10.7554/elife.55582 · 2020
Cannabidiol ameliorates PTSD-like symptoms by inhibiting neuroinflammation through its action on CB2 receptors in the brain of male mice
10.1016/j.bbi.2024.05.016 · 2024
Advances in the study of pharmacotherapy for addiction to naturally-derived psychoactive substances
2025
Targeting cannabinoid type 2 receptors alters human tau levels in ex vivo brain slice cultures
10.1002/alz.093442 · 2024
Developing the cannabinoid receptor 2 (CB2) pharmacopoeia: past, present, and future
10.1016/j.tips.2022.06.010 · 2022
The development and therapeutic potential of classical and next-generation cannabinoid ligands
10.1016/j.phrs.2025.108022 · 2025
Applying structure-based drug design approaches to allosteric modulators of GPCRs
10.1016/j.tips.2017.05.010 · 2017
Biased allosteric modulation in GPCR drug discovery
10.1007/164_2025_771 · 2026
Elucidating biased signaling in class a GPCRs
10.1016/j.tips.2025.10.008 · 2025
Mechanism of β2AR regulation by an intracellular positive allosteric modulator
10.1126/science.aaw8981 · 2019
Antidepressant effects and mechanisms of group II mGlu receptor-specific negative allosteric modulators
10.1016/j.neuron.2019.12.011 · 2020
Structural basis for allosteric agonism of human α7 nicotinic acetylcholine receptors
10.1038/s41421-025-00788-y · 2025
Rational design of neutral allosteric modulators of the CB1 receptor with improved receptor interactions and unique pharmacology
10.1016/j.bpj.2012.11.2278 · 2013
Allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain
10.1016/j.apsb.2023.07.020 · 2024
Structural perspectives on biased allostery of GPCR Signaling
10.1007/164_2025_767 · 2026
State-specific peptide design targeting G protein-coupled receptors
10.1021/acs.jcim.5c00884 · 2025
Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage
10.1038/s41598-017-09808-8 · 2017
In silico prediction and validation of CB2 allosteric binding sites to aid the design of allosteric modulators
10.3390/molecules27020453 · 2022
Design of Negative and Positive Allosteric Modulators of the cannabinoid CB2 receptor derived from the natural product cannabidiol
10.1021/acs.jmedchem.1c00561 · 2021
Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2
10.7554/elife.65834 · 2022
Identification of an unexplored dynamic allosteric site on the activation pathway of the vasopressin V2 receptor
10.1021/acs.jmedchem.5c01619 · 2025
Improving protein-peptide docking results via pose-clustering and rescoring with a combined knowledge-based and MM-GBSA scoring function
10.1021/acs.jcim.0c00058 · 2020
Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism
10.1186/s12859-015-0567-3 · 2015
Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor
10.1016/j.jbc.2024.107330 · 2024
Advances in cannabinoid receptors pharmacology: from receptor structural insights to ligand discovery
10.1038/s41401-024-01472-9 · 2025
Allosterism in the adenosine A2A and cannabinoid CB2 heteromer
10.1111/bph.16502 · 2025
Cryo-EM structure of the human cannabinoid receptor CB2-Gi signaling complex
10.1016/j.cell.2020.01.007 · 2020
Identification of a cannabinoid receptor 2 allosteric site using computational modeling and pharmacological analysis
10.1021/acsptsci.4c00547 · 2025
No additional external references are available.