Abstract
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Tamara Westover, Michael P. Walsh, Sherif Abdelhamed, Emily Xiong, Guangchun Song, Melvin E. Thomas, Masayuki Umeda, Jamie L. Maciaszek, Jasmine C. Wong, Astrid Wintering, Peter D. Emanuel, Mignon L. Loh, Sarah K. Tasian, Elliot Stieglitz, Jason R. Schwartz, Kevin M. Shannon, Jeffery M. Klco
Abstract
Rights: UNKNOWN · cc-by-nc-nd · Source: journal-auto-sync:external:CROSSREF_ISSN
Authors
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Monosomy 7 in pediatric myelodysplastic syndromes
10.1016/j.hoc.2018.04.007 · 2018
Juvenile myelomonocytic leukemia-a comprehensive review and recent advances in management
2021
Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases
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Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis
10.7554/elife.07839 · 2015
The enigma of monosomy 7
10.1182/blood-2017-12-822262 · 2018
The significance of CUX1 and chromosome 7 in myeloid malignancies
10.1097/moh.0000000000000699 · 2022
Genomics of deletion 7 and 7q in myeloid neoplasm: from pathogenic culprits to potential synthetic lethal therapeutic targets
10.1038/s41375-023-02003-x · 2023
Genomic characterization of AML with aberrations of chromosome 7: a multinational cohort of 519 patients
10.1186/s13045-024-01590-1 · 2024
Genomes for kids: the scope of pathogenic mutations in pediatric cancer revealed by comprehensive DNA and RNA sequencing
10.1158/2159-8290.cd-20-1631 · 2021
The genomic landscape of pediatric myelodysplastic syndromes
10.1038/s41467-017-01590-5 · 2017
Institutions
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Provenance
crossref
Confidence 100%
pubmed
Confidence 98%
europepmc
Confidence 96%
unpaywall
Confidence 95%
doaj
Confidence 92%
datacite
Confidence 0%
The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms
10.1038/s41467-021-21255-8 · 2021
Integrated genomic analysis identifies UBTF tandem duplications as a recurrent lesion in pediatric acute myeloid leukemia
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A new genomic framework to categorize pediatric acute myeloid leukemia
10.1038/s41588-023-01640-3 · 2024
SJPedPanel: a pan-cancer gene panel for childhood malignancies to enhance cancer monitoring and early detection
10.1158/1078-0432.ccr-24-1063 · 2024
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10.1038/onc.2014.196 · 2015
CRISPR screening in human hematopoietic stem and progenitor cells reveals an enrichment for tumor suppressor genes within chromosome 7 commonly deleted regions
10.1038/s41375-021-01491-z · 2022
Recurrent genetic defects on chromosome 7q in myeloid neoplasms
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Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis
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10.1038/s41591-021-01511-6 · 2021
Germline SAMD9 and SAMD9L mutations are associated with extensive genetic evolution and diverse hematologic outcomes
10.1172/jci.insight.121086 · 2018
EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations
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The genomic landscape of juvenile myelomonocytic leukemia [published correction appears in Nat Genet. 2015;47(11):1333, Nat Genet. 2016;48(1):101
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Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network
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Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia
10.1084/jem.20180853 · 2021
The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
10.1038/nm.4439 · 2018
5G2 mutant mice model loss of a commonly deleted segment of chromosome 7q22 in myeloid malignancies
10.1038/s41375-024-02205-x · 2024
Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS
10.1182/blood-2017-10-810028 · 2018
High EVI1 expression predicts outcome in younger adult patients with acute myeloid leukemia and is associated with distinct cytogenetic abnormalities
10.1200/jco.2009.26.0646 · 2010
Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2
10.1126/sciadv.adk9076 · 2024
EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs
10.1182/blood-2011-11-393827 · 2012
Single-cell RNA-seq reveals a distinct transcriptome signature of aneuploid hematopoietic cells
10.1182/blood-2017-08-803353 · 2017
Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice
10.1172/jci158869 · 2022
No additional external references are available.