Abstract
Jianan Ye, Sijia Yin, Yutao Lin, Shuhui Yang, Lieen Ma, Kangyang Gao, Yule Wang, Xinhang Yang, Zhichao Yang, Shujun Xu
Abstract
Authors
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No local citing links have been materialized yet.
Alzheimer's disease
10.1136/bmj.b158 · 2009
Pathogenesis of Alzheimer's disease
10.3390/ijms24010107 · 2022
Alzheimer's disease: from immunotherapy to immunoprevention
10.1016/j.cell.2023.08.021 · 2023
HDAC6 in diseases of cognition and of neurons
10.3390/cells10010012 · 2020
Inhibition of histone deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer'S disease: a review (2010-2020)
10.1016/j.ejmech.2021.113874 · 2021
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer'S disease models via HDAC6 inhibition
10.1016/j.phymed.2021.153887 · 2022
TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
10.1016/s1097-2765(02)00450-1 · 2002
An acetylation site in the middle domain of Hsp90 regulates chaperone function
10.1016/j.molcel.2006.12.008 · 2007
Characterization of the two catalytic domains in histone deacetylase 6
10.1016/j.bbrc.2005.12.144 · 2006
Discovery of HDAC6-selective inhibitor NN-390 with in vitro efficacy in group 3 medulloblastoma
Institutions
Provenance
crossref
Confidence 100%
pubmed
Confidence 98%
openalex
Confidence 95%
datacite
Confidence 0%
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Small molecules targeting HDAC6 for cancer treatment: current progress and novel strategies
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Histone deacetylase 6 structure and molecular basis of catalysis and inhibition
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Discovery of novel polysubstituted N-alkyl acridone analogues as histone deacetylase isoform-selective inhibitors for cancer therapy
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Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
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Synthesis and anticancer research of n‐(2-aminophenyl)benzamide acridine derivatives as dual topoisomerase I and isoform-selective HDAC inhibitors
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Synthesis and evaluation of novel N-arylamide-quinoline derivatives as HDAC isoform-selective inhibitors: in vitro and in vivo anticancer efficacy and pharmacokinetic studies
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Target identification using drug affinity responsive target stability (DARTS)
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In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation
10.1093/emboj/cdf682 · 2002
Therapeutic potential of dual HDAC6/SIRT2 inhibition in Alzheimer's disease
10.1016/j.ejmech.2025.117733 · 2025
Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain
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The role of HDAC6 in Alzheimer's disease
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NF-κB in immunobiology
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Recent development of selective inhibitors targeting the HDAC6 as anti-cancer drugs: structure, function and design
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Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation
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Fascaplysin derivatives are potent multitarget agents against Alzheimer's disease: in vitro and in vivo evidence
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PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain
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Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease
10.1093/brain/awz364 · 2020
The Y-maze for assessment of spatial working and reference memory in mice
10.1007/978-1-4939-8994-2_10 · 2019
Retinoic acid receptor is a novel therapeutic target for postoperative cognitive dysfunction
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Retinoic acid receptor is a novel therapeutic target for postoperative cognitive dysfunction
10.3390/pharmaceutics15092311 · doi-reference
The Y-maze for assessment of spatial working and reference memory in mice
10.1007/978-1-4939-8994-2_10 · doi-reference
Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease
10.1093/brain/awz364 · doi-reference
PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain
10.1126/scitranslmed.aba7394 · doi-reference
Fascaplysin derivatives are potent multitarget agents against Alzheimer's disease: in vitro and in vivo evidence
10.1021/acschemneuro.9b00503 · doi-reference
Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation
10.1021/ar8000475 · doi-reference
iClick-Mediated Au(I) functionalization of polystyrene: lighting up polystyrene with phosphorescence
10.1021/acsapm.4c03897 · doi-reference
MCPB.py: a python based metal center parameter builder
10.1021/acs.jcim.5b00674 · doi-reference
Zinc cofactor in human histone deacetylase 8: requirement for function and opportunity for drug discovery
10.1016/j.ijbiomac.2025.149851 · doi-reference
PRODIGY: a web server for predicting the binding affinity of protein-protein complexes
10.1093/bioinformatics/btw514 · doi-reference
Analysing protein complexes in plant science: insights and limitation with AlphaFold 3
10.1186/s40529-025-00462-2 · doi-reference
Recent development of selective inhibitors targeting the HDAC6 as anti-cancer drugs: structure, function and design
10.1016/j.bioorg.2023.106622 · doi-reference
NF-κB in immunobiology
10.1038/cr.2011.13 · doi-reference
The role of HDAC6 in Alzheimer's disease
10.3233/jad-2012-120727 · doi-reference
Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain
10.1016/j.ebiom.2020.102919 · doi-reference
Therapeutic potential of dual HDAC6/SIRT2 inhibition in Alzheimer's disease
10.1016/j.ejmech.2025.117733 · doi-reference
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation
10.1093/emboj/cdf682 · doi-reference
Target identification using drug affinity responsive target stability (DARTS)
10.1073/pnas.0910040106 · doi-reference
Synthesis and evaluation of novel N-arylamide-quinoline derivatives as HDAC isoform-selective inhibitors: in vitro and in vivo anticancer efficacy and pharmacokinetic studies
10.1016/j.bioorg.2026.109877 · doi-reference
Synthesis and anticancer research of n‐(2-aminophenyl)benzamide acridine derivatives as dual topoisomerase I and isoform-selective HDAC inhibitors
10.1002/slct.202001880 · doi-reference
Histone deacetylase 10 structure and molecular function as a polyamine deacetylase
10.1038/ncomms15368 · doi-reference
Discovery of novel polysubstituted N-alkyl acridone analogues as histone deacetylase isoform-selective inhibitors for cancer therapy
10.1080/14756366.2023.2206581 · doi-reference
HDAC6 regulates BACE1 stability and NLRP3 inflammasome activation in Alzheimer's disease
10.1093/brain/awag089 · doi-reference
Histone deacetylase 6 structure and molecular basis of catalysis and inhibition
10.1038/nchembio.2134 · doi-reference
Small molecules targeting HDAC6 for cancer treatment: current progress and novel strategies
10.1016/j.biopha.2024.117218 · doi-reference
Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A
10.1021/ja102758v · doi-reference
HDAC6 as privileged target in drug discovery: a perspective
10.1016/j.phrs.2020.105274 · doi-reference
Discovery of HDAC6-selective inhibitor NN-390 with in vitro efficacy in group 3 medulloblastoma
10.1021/acs.jmedchem.1c01585 · doi-reference
Characterization of the two catalytic domains in histone deacetylase 6
10.1016/j.bbrc.2005.12.144 · doi-reference
An acetylation site in the middle domain of Hsp90 regulates chaperone function
10.1016/j.molcel.2006.12.008 · doi-reference
TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90
10.1016/s1097-2765(02)00450-1 · doi-reference
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer'S disease models via HDAC6 inhibition
10.1016/j.phymed.2021.153887 · doi-reference
Inhibition of histone deacetylase 6 (HDAC6) as a therapeutic strategy for Alzheimer'S disease: a review (2010-2020)
10.1016/j.ejmech.2021.113874 · doi-reference
HDAC6 in diseases of cognition and of neurons
10.3390/cells10010012 · doi-reference
Alzheimer's disease: from immunotherapy to immunoprevention
10.1016/j.cell.2023.08.021 · doi-reference
Pathogenesis of Alzheimer's disease
10.3390/ijms24010107 · doi-reference
Alzheimer's disease
10.1136/bmj.b158 · doi-reference