PM2.5 and the global allergy burden: integrated mechanisms via systemic inflammation and lung microbiome-immune dysregulation

Fine particulate matter induces childhood asthma attacks via extracellular vesicle-packaged Let-7i-5p-mediated modulation of the MAPK signaling pathway

10.1002/advs.202102460 · doi-reference

PM2.5 and serum metabolome and insulin resistance, potential mediation by the gut microbiome: a population-based panel study of older adults in China

10.1289/ehp9688 · doi-reference

Association between air pollution and allergic upper respiratory diseases: a meta-analysis

10.1183/16000617.0266-2024 · doi-reference

The transcription factor XBP1 in dendritic cells promotes the T(H)2 cell response in airway allergy

10.1126/scisignal.abm9454 · doi-reference

Association between ambient fine particulate matter constituents and mortality and morbidity of cardiovascular and respiratory diseases: a systematic review and meta-analysis

10.1016/j.envpol.2025.126476 · doi-reference

PM2.5 promotes macrophage-mediated inflammatory response through airway epithelial cell-derived exosomal miR-155-5p

10.2147/jir.s482509 · doi-reference

PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice

10.1016/j.ecoenv.2021.112433 · doi-reference

Probiotics ameliorates pulmonary inflammation via modulating gut microbiota and rectifying Th17/Treg imbalance in a rat model of PM2.5 induced lung injury

10.1016/j.ecoenv.2022.114060 · doi-reference

Modification of food allergy on the associations between early life exposure to size-specific particulate matter and childhood allergic rhinitis

10.1021/acs.est.3c05532 · doi-reference

PM2.5 Induced Nasal Mucosal Barrier Dysfunction and Epithelial-Mesenchymal Transition to Promote Chronic Rhinosinusitis Through IL4I1-AhR Signaling Pathway

10.3390/toxics13060488 · doi-reference

Pretreatment with rosavin attenuates PM2.5-induced lung injury in rats through antiferroptosis via PI3K/Akt/Nrf2 signaling pathway

10.1002/ptr.7606 · doi-reference

Selenomethionine mitigate PM2.5-induced cellular senescence in the lung via attenuating inflammatory response mediated by cGAS/STING/NF-κB pathway

10.1016/j.ecoenv.2022.114266 · doi-reference

The Lung Microbiota Affects Pulmonary Inflammation and Oxidative Stress Induced by PM(2.5) Exposure

10.1021/acs.est.1c08888 · doi-reference

The effects and pathogenesis of PM2.5 and its components on chronic obstructive pulmonary disease

10.2147/copd.s402122 · doi-reference

The effect of real-ambient PM2.5 exposure on the lung and gut microbiomes and the regulation of Nrf2

10.1016/j.ecoenv.2023.114702 · doi-reference

The intersect of genetics, environment, and microbiota in asthma-perspectives and challenges

10.1016/j.jaci.2020.08.026 · doi-reference

Neutral polysaccharide from platycodonis radix-ameliorated PM(2.5)-induced lung injury by inhibiting the TLR4/NF-κB p65 pathway and regulating the lung and gut microbiome

10.1021/acs.jafc.4c07319 · doi-reference

RoB 2: a revised tool for assessing risk of bias in randomised trials

10.1136/bmj.l4898 · doi-reference

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

10.1136/bmj.i4919 · doi-reference

Lactobacillus rhamnosus probiotic prevents airway function deterioration and promotes gut microbiome resilience in a murine asthma model

10.1080/19490976.2020.1766345 · doi-reference

Stop searching and you will find it: Search-Resistant Concepts in systematic review searches

10.1136/bmjebm-2023-112798 · doi-reference

Salidroside prevents PM2.5-induced BEAS-2B cell apoptosis via SIRT1-dependent regulation of ROS and mitochondrial function

10.1016/j.ecoenv.2022.113170 · doi-reference

Food allergy across the globe

10.1016/j.jaci.2021.10.018 · doi-reference

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

10.1186/s12915-014-0087-z · doi-reference

Development of the SciRAP approach for evaluating the reliability and relevance of in vitro toxicity data

10.3389/ftox.2021.746430 · doi-reference

Early life microbial exposures and allergy risks: opportunities for prevention

10.1038/s41577-020-00420-y · doi-reference

Subchronic exposure to concentrated ambient PM2.5 perturbs gut and lung microbiota as well as metabolic profiles in mice

10.1016/j.envpol.2020.115987 · doi-reference

PM2.5 exposure regulates Th1/Th2/Th17 cytokine production through NF-κB signaling in combined allergic rhinitis and asthma syndrome

10.1016/j.intimp.2023.110254 · doi-reference

Butyrate as a bioactive human milk protective component against food allergy

10.1111/all.14625 · doi-reference

The gut-lung axis: a new perspective on the impact of atmospheric particulate matter exposure on chronic obstructive pulmonary disease

10.3389/fimmu.2025.1657675 · doi-reference

Particulate matter exposure is associated with increased inflammatory cytokines and eosinophils in chronic rhinosinusitis

10.1111/all.16006 · doi-reference

Fudosteine attenuates lung inflammation in mice with PM2.5-induced asthma exacerbation by inhibiting pyroptosis via the NLRP3/caspase-1/GSDMD pathway

10.1016/j.taap.2025.117346 · doi-reference

Comparing human exposure to fine particulate matter in low and high-income countries: a systematic review of studies measuring personal PM2.5 exposure

10.1016/j.scitotenv.2022.155207 · doi-reference

Chemical constituents of PM2.5 and their association with childhood asthma and lung function: a systematic review and meta-analysis

10.1007/s00431-025-06214-5 · doi-reference

PM(2.5) exacerbates nasal epithelial barrier damage in allergic rhinitis mice: A crosstalk between gut microbiota and NLRP3 inflammsome

10.1016/j.ecoenv.2025.118140 · doi-reference

PM2.5 exposure perturbs lung microbiome and its metabolic profile in mice

10.1016/j.scitotenv.2020.137432 · doi-reference

Respiratory benefits of multisetting air purification in children: a cluster randomized crossover trial

10.1001/jamapediatrics.2024.5049 · doi-reference

Does ambient PM2.5 reduce the protective association of leisure-time physical activity with mortality? A systematic review, meta-analysis, and individual-level pooled analysis of cohort studies involving 1.5 million adults

10.1186/s12916-025-04496-y · doi-reference

Long-term exposure to elemental carbon and disease incidence: a systematic review and meta-analysis

10.1186/s12940-025-01209-z · doi-reference

A novel herbal extract blend product prevents particulate matters-induced inflammation by improving gut microbiota and maintaining the integrity of the intestinal barrier

10.3390/nu14102010 · doi-reference