From single metals to mixtures: uncovering genetic risk factors for metal exposure in disease-free individuals from the EPIC-Spain cohort

Associations between individual and mixed urinary metal exposure and dyslipidemia among Chinese adults: data from the China Multi-Ethnic Cohort Study

10.1016/j.ecoenv.2024.116696 · doi-reference

Causal relationship between blood metal levels and breast cancer risk: a Mendelian randomization study in East Asian populations

10.1007/s12672-025-03608-7 · doi-reference

Genome-wide association and Mendelian randomization study of blood copper levels and 213 deep phenotypes in humans

10.1038/s42003-022-03351-7 · doi-reference

Genetic analysis the causal associations between metal elements and thyroid cancer: a bidirectional Mendelian randomization

10.1007/s12672-025-03143-5 · doi-reference

A review of toxicity and mechanisms of individual and mixtures of heavy metals in the environment

10.1007/s11356-016-6333-x · doi-reference

Metalloestrogens exposure and risk of gestational diabetes mellitus: evidence emerging from the systematic review and meta-analysis

10.1016/j.envres.2024.118321 · doi-reference

Molecular mechanisms of environmental exposures and human disease

10.1038/s41576-022-00569-3 · doi-reference

European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection

10.1079/phn2002394 · doi-reference

DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants

10.1093/nar/gkw943 · doi-reference

Prediagnostic levels of copper and zinc and breast cancer risk in the ORDET cohort

10.1158/1055-9965.epi-21-1252 · doi-reference

Metals and breast cancer risk: a prospective Study using toenail biomarkers

10.1093/aje/kwab204 · doi-reference

Genome-wide association study of toxic metals and trace elements reveals novel associations

10.1093/hmg/ddv190 · doi-reference

A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans

10.1038/s42003-024-06101-z · doi-reference

Genetic disorders affecting proteins of iron and copper metabolism: clinical implications

10.2169/internalmedicine.41.762 · doi-reference

Human blood-based exposure levels of persistent organic pollutant (POP) mixtures antagonise androgen receptor transactivation and translocation

10.1016/j.envint.2019.105083 · doi-reference

A state-of-the-science review on metal biomarkers

10.1007/s40572-023-00402-x · doi-reference

Association of both prenatal and early childhood multiple metals exposure with neurodevelopment in infant: a prospective cohort study

10.1016/j.envres.2021.112450 · doi-reference

Association between heavy metal exposure and heart failure incidence and mortality: insights from NHANES data (2003–2018)

10.1186/s12889-025-23177-2 · doi-reference

Association between mixed heavy metal exposure and arterial stiffness, with alkaline phosphatase identified as a mediator

10.1007/s12011-024-04359-2 · doi-reference

Temporal variability of blood lead, mercury, and cadmium levels in elderly panel study (2008–2014)

10.1016/j.ijheh.2016.11.014 · doi-reference

The impact of genetic variation on metabolism of heavy metals: genetic predisposition?

10.1016/j.biopha.2019.108642 · doi-reference

The role of copper and zinc in irritable bowel syndrome: a mendelian randomization study

10.1093/aje/kwab180 · doi-reference

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

10.1093/carcin/bgv039 · doi-reference

[the European prospective investigation about cancer and nutrition (EPIC)]

10.1590/s1135-57272004000200004 · doi-reference

Cadmium induces iron deficiency anemia through the suppression of iron transport in the duodenum

10.1016/j.toxlet.2020.07.005 · doi-reference

Using transcriptomic signatures to elucidate individual and mixture effects of inorganic arsenic and manganese in human placental trophoblast HTR-8/SVneo cells

10.1093/toxsci/kfae147 · doi-reference

Genome-wide association study identifies loci affecting blood copper, selenium and zinc

10.1093/hmg/ddt239 · doi-reference

Next-generation genotype imputation service and methods

10.1038/ng.3656 · doi-reference

Tutorial: a guide to performing polygenic risk score analyses

10.1038/s41596-020-0353-1 · doi-reference

The NHGRI-EBI GWAS catalog: standards for reusability, sustainability and diversity

10.1093/nar/gkae1070 · doi-reference

A critical review on the interactions of microplastics with heavy metals: mechanism and their combined effect on organisms and humans

10.1016/j.scitotenv.2021.147620 · doi-reference

Functional mapping and annotation of genetic associations with FUMA

10.1038/s41467-017-01261-5 · doi-reference

Diet and cancer — the European prospective investigation into cancer and nutrition

10.1038/nrc1298 · doi-reference

Genetic effects on gene expression across human tissues

10.1038/nature24277 · doi-reference