Abstract
Cinzia Campus, Carla Serri, Marta Roldo, Paolo Giunchedi, Elisabetta Gavini, Giovanna Rassu
Abstract
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Nose-to-brain drug delivery: an update on clinical challenges and progress towards approval of anti-Alzheimer drugs
10.1016/j.jconrel.2018.05.011 · 2018
In vitro comparative study of solid lipid and PLGA nanoparticles designed to facilitate nose-to-brain delivery of insulin
10.3390/ijms222413258 · 2021
The cell-penetrating peptide tat facilitates effective internalization of PSD-95 inhibitors into blood–brain barrier endothelial cells but less efficient permeation across the blood–brain barrier in vitro and in vivo
10.3389/fddev.2022.854703 · 2022
Nose-to-brain delivery of therapeutic peptides as nasal aerosols
10.3390/pharmaceutics14091870 · 2022
Resistance to antibiotics: are we in the post-antibiotic era?
10.1016/j.arcmed.2005.06.009 · 2005
Topical cathelicidin (LL‐37) an innate immune peptide induces acute olfactory epithelium inflammation in a mouse model
10.1002/alr.21634 · 2015
How can biomaterial-conjugated antimicrobial peptides fight bacteria and be protected from degradation?
10.1016/j.actbio.2024.04.043 · 2024
Intranasal drug delivery: unlocking the nose-to-brain route for central nervous system therapies
2026
Stimuli‐responsive delivery of antimicrobial peptides using polyelectrolyte complexes
unpaywall
Confidence 95%
datacite
Confidence 0%
10.1002/mabi.202300123 · 2023
Antimicrobial peptides
10.3390/ph6121543 · 2013
LL-37: structures, antimicrobial activity, and influence on amyloid-related diseases
10.3390/biom14030320 · 2024
Antimicrobial peptides: an update on classifications and databases
10.3390/ijms222111691 · 2021
Using nanotechnology to deliver biomolecules from nose to brain — peptides, proteins, monoclonal antibodies and RNA
10.1007/s13346-021-01086-2 · 2022
Intranasal peptide therapeutics: a promising avenue for overcoming the challenges of traditional CNS drug development
10.3390/cells11223629 · 2022
Antimicrobial peptide Temporin-L complexed with anionic cyclodextrins results in a potent and safe agent against sessile bacteria
10.1016/j.ijpharm.2020.119437 · 2020
Role of glial cells in the functional expression of LL-37/Rat cathelin-related antimicrobial peptide in meningitis
10.1097/nen.0b013e31818b4801 · 2008
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?
10.1038/nrmicro1098 · 2005
Immunomodulatory and anti-inflammatory activity in vitro and in vivo of a novel antimicrobial candidate
10.1074/jbc.m116.750257 · 2016
Antimicrobial peptides: opportunities and challenges in overcoming resistance
10.1016/j.micres.2024.127822 · 2024
Systematic review and meta‐analysis of reported adverse events of long‐term intranasal oxytocin treatment for autism spectrum disorder
10.1111/pcn.12627 · 2018
Electrospun mucoadhesive nanofibrous films for intranasal delivery of propranolol hydrochloride for migraine prophylaxis
10.1016/j.jddst.2025.107552 · 2025
Surface physical activity and hydrophobicity of designed helical peptide amphiphiles control their bioactivity and cell selectivity
10.1021/acsami.6b08297 · 2016
The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery
10.1016/j.addr.2016.01.022 · 2016
Recognition of pathogenic microbes by the drosophila phagocytic pattern recognition receptor eater
10.1074/jbc.m110.214007 · 2011
10.1089/jamp.2024.0058
10.1089/jamp.2024.0058
10.4018/978-1-7998-9414-8.ch007
10.4018/978-1-7998-9414-8.ch007
Bacteriocins — a viable alternative to antibiotics?
10.1038/nrmicro2937 · 2013
Inhalable polymeric nanoparticles for pulmonary delivery of antimicrobial peptide SET-M33: antibacterial activity and toxicity in vitro and in vivo
10.3390/pharmaceutics15010003 · 2022
Temporins: multifunctional peptides from frog skin
10.3390/ijms24065426 · 2023
10.1039/d4pm00057a
10.1039/d4pm00057a
Chitosan-coated liposomes for intranasal delivery of ghrelin: enhancing bioavailability to the central nervous system
10.3390/pharmaceutics17111493 · 2025
Antibiotic failure: beyond antimicrobial resistance
10.1016/j.drup.2023.101012 · 2023
Antimicrobial peptide delivery systems as promising tools against resistant bacterial infections
10.3390/antibiotics13111042 · 2024
Advances in the delivery and application of antimicrobial peptide-based nanomaterials
10.1016/j.cej.2024.154232 · 2024
Unresolved referenced work
Kept as external metadata until matched
Antimicrobial peptide-loaded nanoparticles as inhalation therapy for P. aeruginosa infections
10.2147/ijn.s218966 · 2020
Structural and functional effects of the interaction between an antimicrobial peptide and its analogs with model bacterial and erythrocyte membranes
10.3390/biom15081143 · 2025
Design and characterization of a nasal thermogelling system loaded with tolperisone for the treatment of cerebral arteriosclerosis through the nose to brain delivery system
10.1007/s10971-025-06906-2 · 2025
Bridging the blood-brain barrier: strategies to improve delivery of biologics to tumors in the brain
10.1186/s12987-026-00760-2 · 2026
De novo design of Na+-activated lipopeptides with selective antifungal activity: a promising strategy for antifungal drug discovery
10.1016/j.ijbiomac.2024.137894 · 2024
Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections
10.1002/med.21879 · doi-reference
Gelatin nanostructured lipid carriers-mediated intranasal delivery of basic fibroblast growth factor enhances functional recovery in hemiparkinsonian rats
10.1016/j.nano.2013.10.009 · doi-reference
Transnasal-brain delivery of nanomedicines for neurodegenerative diseases
10.3389/fddev.2023.1247162 · doi-reference
Intranasal nanoparticles of basic fibroblast growth factor for brain delivery to treat Alzheimer’s disease
10.1016/j.ijpharm.2013.11.049 · doi-reference
Antimicrobial peptides of multicellular organisms
10.1038/415389a · doi-reference
Broad-spectrum antiviral activity of the amphibian antimicrobial peptide temporin L and its analogs
10.3390/ijms23042060 · doi-reference
A review of the resistance mechanisms for β-lactams, macrolides and fluoroquinolones among Streptococcus pneumoniae
10.3390/medicina59111927 · doi-reference
Feasibility of intranasal delivery of thin-film freeze-dried, mucoadhesive vaccine powders
10.1016/j.ijpharm.2023.122990 · doi-reference
Multifunctional cationic host defence peptides and their clinical applications
10.1007/s00018-011-0710-x · doi-reference
Bacteria-targeting nanoparticles with microenvironment-responsive antibiotic release to eliminate intracellular S. aureus and associated infection
10.1021/acsami.7b15678 · doi-reference
Discovery of melittin as triple-action agent: broad-spectrum antibacterial, anti-biofilm, and potential anti-quorum sensing activities
10.3390/molecules29030558 · doi-reference
Cell-penetrating peptide-modified PLGA nanoparticles for enhanced nose-to-brain macromolecular delivery
10.1007/s13233-013-1029-2 · doi-reference
Intranasal brain delivery of cationic nanoemulsion-encapsulated TNFα siRNA in prevention of experimental neuroinflammation
10.1016/j.nano.2015.12.374 · doi-reference
Nose-to-brain delivery of targeted lipid nanoparticles as two-pronged β-amyloid nanoscavenger for Alzheimer’s disease therapy
10.1016/j.apsb.2025.02.035 · doi-reference
Bacterial resistance to antibiotics: enzymatic degradation and modification
10.1016/j.addr.2005.04.002 · doi-reference
An overview of in vitro and in vivo techniques for characterization of intranasal protein and peptide formulations for brain targeting
10.1016/j.ijpharm.2024.123922 · doi-reference
Comparison of intranasal steroid application using nasal saline irrigation and a mucosal atomization device to treat chronic rhinosinusitis
10.1089/jamp.2020.1644 · doi-reference
Self-assembled nanostructured antimicrobial peptides: design strategies, structures, mechanism and therapeutic applications
10.1039/d5tb01872b · doi-reference
10.1093/nar/gkaf860
10.1093/nar/gkaf860 · doi-reference
Improved methods for classification, prediction, and design of antimicrobial peptides
10.1007/978-1-4939-2285-7_3 · doi-reference
Antimicrobial peptides of the cathelicidin family: focus on LL-37 and its modifications
10.3390/ijms26168103 · doi-reference
Synthetic therapeutic peptides: science and market
10.1016/j.drudis.2009.10.009 · doi-reference
Exploring molecular mechanisms of drug resistance in bacteria and progressions in CRISPR/Cas9-based genome expurgation solutions
10.1016/j.gmg.2025.100042 · doi-reference
Current advances in lipid and polymeric antimicrobial peptide delivery systems and coatings for the prevention and treatment of bacterial infections
10.3390/pharmaceutics13111840 · doi-reference
Reservoir-type intranasal implants for sustained release of risperidone: a potential alternative for long-term treatment of schizophrenia
10.1016/j.jddst.2024.105973 · doi-reference
Antimicrobial peptides as anticancer agents: functional properties and biological activities
10.3390/molecules25122850 · doi-reference
Antimicrobial multidrug resistance and mechanisms of action: an overview
10.1155/bmri/8847267 · doi-reference
Antimicrobial resistance (AMR)
10.3389/bjbs.2023.11387 · doi-reference
mRNA-laden lipid-nanoparticle-enabled in situ CAR-macrophage engineering for the eradication of multidrug-resistant bacteria in a sepsis mouse model
10.1021/acsnano.3c10109 · doi-reference
Antimicrobial peptides in the brain
10.1007/s00005-010-0089-7 · doi-reference
Evaluation of drug permeation enhancement by using in vitro and ex vivo models
10.3390/ph18020195 · doi-reference
Poly(caprolactone)-based coatings on 3D-printed biodegradable implants: a novel strategy to prolong delivery of hydrophilic drugs
10.1021/acs.molpharmaceut.0c00515 · doi-reference
Sequence and specificity of two antibacterial proteins involved in insect immunity
10.1038/292246a0 · doi-reference
Blood-brain barrier transport of short proline-rich antimicrobial peptides
10.2174/09298665113206660110 · doi-reference
Expression of antimicrobial host defence peptides in the central nervous system during health and disease
10.1093/discim/kyac003 · doi-reference
New perspectives on old and new therapies of staphylococcal skin infections: the role of biofilm targeting in wound healing
10.3390/antibiotics10111377 · doi-reference
Novel design of simplified β-hairpin antimicrobial peptide as a potential food preservative based on Trp-pocket backbone
10.1016/j.foodchem.2024.139128 · doi-reference
Development and evaluation of olanzapine-loaded PLGA nanoparticles for nose-to-brain delivery: in vitro and in vivo studies
10.1016/j.actbio.2011.07.025 · doi-reference
Development of thermosensitive chitosan/glicerophospate injectable in situ gelling solutions for potential application in intraoperative fluorescence imaging and local therapy of hepatocellular carcinoma: a preliminary study
10.1517/17425247.2015.1042452 · doi-reference
Chitosan-coated liposome dry-powder formulations loaded with ghrelin for nose-to-brain delivery
10.1016/j.ejpb.2018.06.011 · doi-reference