Type 1 diabetes aetiology and pathogenesis – A new hypothesis

The pathogenic "symphony" in type 1 diabetes: a disorder of the immune system, beta cells, and exocrine pancreas

10.1016/j.cmet.2023.06.018 · doi-reference

Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans

10.2337/db07-1369 · doi-reference

Actual distribution of the number and volume of the islets of Langerhans in different size classes in non-diabetic humans of varying ages

10.1038/1841498a0 · doi-reference

Thyroiditis in the BB rat is associated with lymphopenia but occurs independently of diabetes

10.1016/0896-8411(95)90004-7 · doi-reference

The NOD mouse beyond autoimmune diabetes

10.3389/fimmu.2022.874769 · doi-reference

Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse

10.2337/diabetes.48.5.989 · doi-reference

The postnatal maternal environment influences diabetes development in nonobese diabetic mice

10.1016/j.jaut.2006.11.006 · doi-reference

GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility

10.1038/s41467-021-21015-8 · doi-reference

Heritability of Addison's disease and prevalence of associated autoimmunity in a cohort of 112,100 Swedish twins

10.1007/s12020-017-1441-z · doi-reference

Illuminating the complete ss-cell mass of the human pancreas- signifying a new view on the islets of Langerhans

10.1038/s41467-024-47686-7 · doi-reference

Loss of insulin-positive cell clusters precedes the decrease in islet frequency and beta-cell area in type 1 diabetes

10.2337/db25-0326 · doi-reference

Pancreatic beta-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis

10.1371/journal.pone.0022485 · doi-reference

NOD x 129.H2(g7) backcross delineates 129S1/SvImJ-derived genomic regions modulating type 1 diabetes development in mice

10.2337/db09-0120 · doi-reference

Segregation of autoimmune type 1 diabetes in a cross between diabetic BB and brown Norway rats

10.1006/jaut.1996.0105 · doi-reference

Geospatial clustering of type 1 diabetes in Sweden: a cohort study based on all residential locations from birth to diagnosis

10.1007/s00125-026-06675-9 · doi-reference

Activation pathways that drive CD4(+) T cells to break tolerance in autoimmune diseases

10.1111/imr.13071 · doi-reference

The rise and fall of a paradigm and conceiving a new hypothesis for type 1 diabetes

10.1007/s00125-025-06610-4 · doi-reference

Endocrine pancreas development: effects of metabolic and intergenerational programming caused by a protein-restricted diet

10.1097/mpa.0b013e3182236320 · doi-reference

Current concepts on the pathogenesis of type 1 diabetes--considerations for attempts to prevent and reverse the disease

10.2337/dc15-0144 · doi-reference

Neonatal diabetes mellitus

10.1056/nejm199601043340118 · doi-reference

Genetic overlap between type 1 diabetes and other autoimmune diseases

10.1007/s00281-021-00885-6 · doi-reference

Extended family history of type 1 diabetes and phenotype and genotype of newly diagnosed children

10.2337/dc12-0445 · doi-reference

10.1007/bf00265396

10.1007/bf00265396 · doi-reference

Diabetes and gender

10.1007/s001250051573 · doi-reference

The incidence of diabetes among 0-34 year olds in Sweden: new data and better methods

10.1007/s00125-014-3225-9 · doi-reference

Reversion of β-cell autoimmunity changes risk of type 1 diabetes: TEDDY study

10.2337/dc16-0181 · doi-reference

Next-generation sequencing reveals that HLA-DRB3, -DRB4, and -DRB5 may be associated with islet autoantibodies and risk for childhood type 1 diabetes

10.2337/db15-1115 · doi-reference

Next-generation sequencing reveals additional HLA class I and class II alleles associated with type 1 diabetes and age at onset

10.3389/fimmu.2024.1427349 · doi-reference

Clinical characteristics in Swedish children with and without autoantibodies at the time of type 1 diabetes diagnosis

10.2337/dc25-0840 · doi-reference

Islet cell antibodies (ICA) identify autoimmunity in children with new onset diabetes mellitus negative for other islet cell antibodies

10.1111/pedi.12093 · doi-reference

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

10.1073/pnas.0705894104 · doi-reference

Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma

10.1089/dna.1994.13.505 · doi-reference

Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10

10.1073/pnas.88.19.8337 · doi-reference

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

10.1038/347151a0 · doi-reference

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins

10.1038/298167a0 · doi-reference

Insulin antibodies in insulin-dependent diabetics before insulin treatment

10.1126/science.6362005 · doi-reference

Islet-cell-surface antibodies in juvenile diabetes mellitus

10.1056/nejm197808242990802 · doi-reference

Antibodies to pancreatic islet cells in insulin-dependent diabetics with coexistent autoimmune disease

10.1016/s0140-6736(74)90281-5 · doi-reference

Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies

10.1016/s0140-6736(74)90140-8 · doi-reference

HL-A antigens and diabetes mellitus

10.1016/s0140-6736(74)91201-x · doi-reference