A 6His-2Flag dual-tag strategy enables high-yield production of antimicrobial peptide N6 in Pichia pastoris to combat multidrug-resistant Klebsiella pneumonia

Polymyxin B combinations with FDA-approved non-antibiotic phenothiazine drugs targeting multi-drug resistance of Gram-negative pathogens

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C-terminal mini-PEGylation of a marine peptide N6 had potent antibacterial and anti-inflammatory properties against Escherichia coli and Salmonella strains in vitro and in vivo

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The transcriptomic response of Acinetobacter baumannii to colistin and doripenem alone and in combination in an in vitro pharmacokinetics/pharmacodynamics model

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Interactions of polymyxin B with lipopolysaccharide-containing membranes

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Colibactin contributes to the hypervirulence of pks+ K1 CC23 Klebsiella pneumoniae in mouse meningitis infections

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High BMP7 expression May worsen airway disease in COPD by altering epithelial cell behavior

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Klebsiella pneumoniae-OMVs activate death-signaling pathways in human bronchial epithelial host cells (BEAS-2B)

10.1016/j.heliyon.2024.e29017 · doi-reference

Functional insights from KpfR, a new transcriptional regulator of fimbrial expression that is crucial for Klebsiella pneumoniae pathogenicity

10.3389/fmicb.2020.601921 · doi-reference

Exploration of antimicrobial peptides in the treatment of gentamicin-resistant Klebsiella pneumoniae infection

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The influence of biofilms in the biology of plasmids

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Analysis of antibiotic-induced drug resistance of Salmonella enteritidis and its biofilm formation mechanism

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RmpA regulation of capsular polysaccharide biosynthesis in Klebsiella pneumoniae CG43

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An assessment of siderophore production, mucoviscosity, and mouse infection models for defining the virulence spectrum of hypervirulent Klebsiella pneumoniae

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Enterobactin biosynthesis in Escherichia coli: isochorismate lyase (entB) is a bifunctional enzyme that is phosphopantetheinylated by entD and then acylated by entE using ATP and 2,3-dihydroxybenzoate

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Biofilm formation in a hydrodynamic environment by novel fimh variants and ramifications for virulence

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Conformational ensembles in Klebsiella pneumoniae FimH impact uropathogenesis

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SPR741, Double- or triple-combined with Erythromycin and Clarithromycin, combats drug-resistant Klebsiella pneumoniae, its biofilms, and persister cells

10.3389/fcimb.2022.858606 · doi-reference

An experimental study to evaluate the effect of polymixin E (Colistin) alone or in combination with gentamicin in McCarey-Kaufman corneal preservation medium on various drug resistant bacterial and fungal isolates

10.4103/ijo.ijo_12_22 · doi-reference

Improved stability and activity of a marine peptide-N6NH2 against Edwardsiella tarda and its preliminary application in fish

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How macrolide antibiotics work

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Gentamicin in 1978

10.7326/0003-4819-89-4-528 · doi-reference

Unveiling a new antimicrobial peptide with efficacy against P. aeruginosa and K. pneumoniae from mangrove-derived Paenibacillus thiaminolyticus NNS5-6 and genomic analysis

10.3390/antibiotics13090846 · doi-reference

Antimicrobial activity of two novel antimicrobial peptides AA139 and SET-M33 against clinically and genotypically diverse Klebsiella pneumoniae isolates with differing antibiotic resistance profiles

10.1016/j.ijantimicag.2019.05.019 · doi-reference

Detection of colistin-resistant populations prior to antibiotic exposure in KPC-2-producing Klebsiella pneumoniae clinical isolates

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In vitro pharmacodynamics of colistin against multidrug-resistant Klebsiella pneumoniae

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The One Health stewardship of colistin as an antibiotic of last resort for human health in South Africa

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Designing and optimizing new antimicrobial peptides: all targets are not the same

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Unlocking the power of antimicrobial peptides: advances in production, optimization, and therapeutics

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A novel pH-responsive iron oxide core-shell magnetic mesoporous silica nanoparticle (M-MSN) system encapsulating doxorubicin (DOX) and glucose oxidase (Gox) for pancreatic cancer treatment

10.2147/ijn.s436253 · doi-reference

A recombinant fungal defensin-like peptide-p2 combats multidrug-resistant Staphylococcus aureus and biofilms

10.1007/s00253-019-09785-0 · doi-reference

Comparison of three different in vitro methods of detecting synergy: time-kill, checkerboard, and E test

10.1128/aac.40.8.1914 · doi-reference

Dermatophytic defensin with antiinfective potential

10.1073/pnas.1201263109 · doi-reference

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

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High prevalence of KPC-2-producing hypervirulent Klebsiella pneumoniae causing meningitis in Eastern China

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A new high-yielding antimicrobial peptide NZX and its antibacterial activity against Staphylococcus hyicus in Vitro/Vivo

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Mechanisms of antibiotic resistance and developments in therapeutic strategies to combat Klebsiella pneumoniae infection

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Characterization of an anti-FLAG antibody binding protein in V. cholerae

10.1016/j.bbrc.2020.05.169 · doi-reference

High-yield preparation of American oyster defensin (AOD) via a small and acidic fusion tag and its antibacterial activity against Staphylococcus epidermidis

10.3390/md22010008 · doi-reference

New developments in Pichia pastoris expression system, review and update

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Expression and purification of antimicrobial peptide AP2 using SUMO fusion partner technology in Escherichia coli

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