FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis
10.1038/cr.2014.151 · doi-reference
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
10.1016/j.molcel.2021.03.009 · doi-reference
mTORC1 promotes cell growth via m6A-dependent mRNA degradation
10.1016/j.molcel.2021.03.010 · doi-reference
Nuclear m6A reader YTHDC1 regulates mRNA splicing
10.1016/j.molcel.2016.01.012 · doi-reference
Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer
10.1038/s41467-024-51252-6 · doi-reference
Evolution and biological roles of alternative 3′UTRs
10.1016/j.tcb.2015.10.012 · doi-reference
Long-read Ribo-STAMP simultaneously measures transcription and translation with isoform resolution
10.1101/gr.279176.124 · doi-reference
Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
10.1038/nrm.2017.103 · doi-reference
DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing
10.1016/j.cmet.2021.09.008 · doi-reference
TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis
10.1016/j.cmet.2024.04.003 · doi-reference
A splice-switching oligonucleotide treatment ameliorates glycogen storage disease type 1a in mice with G6PC c.648G>T
10.1172/jci163464 · doi-reference
Subcutaneous adipose tissue splice quantitative trait loci reveal differences in isoform usage associated with cardiometabolic traits
10.1016/j.ajhg.2021.11.019 · doi-reference
Genetic regulation of RNA splicing in human pancreatic islets
10.1186/s13059-022-02757-0 · doi-reference
Regulation of endocrine cell alternative splicing revealed by single-cell RNA sequencing in type 2 diabetes pathogenesis
10.1038/s42003-024-06475-0 · doi-reference
Global prevalence, incidence, and outcomes of non-obese or lean non-alcoholic fatty liver disease: a systematic review and meta-analysis
10.1016/s2468-1253(20)30077-7 · doi-reference
Dysregulation of RNA splicing in early non-alcoholic fatty liver disease through hepatocellular carcinoma
10.1038/s41598-024-52237-7 · doi-reference
De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health
10.1038/ncomms2537 · doi-reference
Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects
10.2337/db07-0156 · doi-reference
Regulation of alternative splicing by histone modifications
10.1126/science.1184208 · doi-reference
HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes
10.1016/j.cmet.2025.07.007 · doi-reference
Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis
10.1016/j.cmet.2011.06.007 · doi-reference
Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation
10.1016/j.cell.2022.12.004 · doi-reference
Dysregulated RNA polyadenylation contributes to metabolic impairment in non-alcoholic fatty liver disease
10.1093/nar/gkac165 · doi-reference
Targeting hepatic serine-arginine protein kinase 2 ameliorates alcohol-associated liver disease by alternative splicing control of lipogenesis
10.1097/hep.0000000000000433 · doi-reference
SRSF10 plays a role in myoblast differentiation and glucose production via regulation of alternative splicing
10.1016/j.celrep.2015.10.038 · doi-reference
SRSF10 regulates alternative splicing and is required for adipocyte differentiation
10.1128/mcb.01674-13 · doi-reference
The RNA-binding protein NONO coordinates hepatic adaptation to feeding
10.1016/j.cmet.2017.12.010 · doi-reference
Adipose HuR protects against diet-induced obesity and insulin resistance
10.1038/s41467-019-10348-0 · doi-reference
The RNA-binding protein HuR is a negative regulator in adipogenesis
10.1038/s41467-019-14001-8 · doi-reference
AMP-activated protein kinase-regulated phosphorylation and acetylation of importin α1: involvement in the nuclear import of RNA-binding protein HuR
10.1074/jbc.m409014200 · doi-reference
AMP-activated kinase regulates cytoplasmic HuR
10.1128/mcb.22.10.3425-3436.2002 · doi-reference
S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase
10.1053/j.gastro.2006.04.019 · doi-reference
Post-transcriptional regulation of de novo lipogenesis by mTORC1-S6K1-SRPK2 signaling
10.1016/j.cell.2017.10.037 · doi-reference
High-density lipoprotein endocytosis by scavenger receptor SR-BII is clathrin-dependent and requires a carboxyl-terminal dileucine motif
10.1074/jbc.m513154200 · doi-reference
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice
10.1038/s42255-022-00681-y · doi-reference
SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high-density lipoprotein and cells
10.1074/jbc.273.24.15241 · doi-reference
Hepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice
10.1371/journal.pone.0115028 · doi-reference
FXR isoforms control different metabolic functions in liver cells via binding to specific DNA motifs
10.1053/j.gastro.2020.07.036 · doi-reference
