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Privacy-aware community infrastructureJ Honkavaara, E Lindh, H Turunen, T Mäki, E Välimäki, V Reunanen, N Vartia
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2023
vivo quantification of muscle damage in dogs after intramuscular administration of drugs
10.1016/s0007-1935(95)80010-7 · 1995
Pharmacokinetics of cefuroxime after intravenous, intramuscular, and subcutaneous administration to dogs
10.1111/jvp.12239 · 2016
Comparison of premedication with or without vatinoxan, co-administered with medetomidine and methadone, in anesthetized dogs
10.1016/j.rvsc.2025.105958 · 2025
The role of active transport in the transcellular movement of the peripheral α2-adrenoceptor antagonist, MK-467: An in vitro pilot study
2017
Vertebral scale system to measure canine heart size in radiographs
10.2460/javma.1995.206.02.194 · 1995
The effect of intravenous maropitant on blood pressure in healthy awake and anesthetized dogs
10.1371/journal.pone.0229736 · 2020
Effects of orally administered enalapril on blood pressure and hemodynamic response to vasopressors during isoflurane anesthesia in healthy dogs
10.1111/vaa.12338 · 2016
Comparison Between Medetomidine and a Medetomidine-Vatinoxan Combination on Cardiorespiratory Variables in Dogs Undergoing Ovariectomy Anesthetized with Butorphanol, Propofol and Sevoflurane or Desflurane
unpaywall
Confidence 95%
datacite
Confidence 0%
10.3390/ani14223322 · 2024
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The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
2020
Effects of a peripheral alpha2 adrenergic-receptor antagonist on the hemodynamic changes induced by medetomidine administration in conscious dogs
10.2460/ajvr.69.6.728 · 2008
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10.1117/1.jbo.18.12.127004 · 2013
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10.1111/j.1365-2885.2010.01242.x · 2011
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Speed-resolved perfusion imaging using multi-exposure laser speckle contrast imaging and machine learning
10.1117/1.jbo.28.3.036007 · 2023
Clinical pharmacology of methadone in dogs
10.1111/j.1467-2995.2009.00476.x · 2010
Peripheral α2-adrenoceptor antagonism affects the absorption of intramuscularly coadministered drugs
10.1016/j.vaa.2018.01.008 · 2018
Peripherally acting α-adrenoceptor antagonist MK-467 with intramuscular medetomidine and butorphanol in dogs: A prospective, randomised, clinical trial
10.1016/j.tvjl.2018.08.007 · 2018
Nausea: current knowledge of mechanisms, measurement and clinical impact
10.1016/j.tvjl.2014.10.007 · 2015
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10.1016/j.tvjl.2018.08.001 · 2018
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Diagnostic value of vertebral left atrial size as determined from thoracic radiographs for assessment of left atrial size in dogs with myxomatous mitral valve disease
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10.1016/j.vaa.2017.05.004 · 2017
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10.1111/j.1467-2995.2005.00233.x · 2005
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10.1016/s1053-0770(98)90197-5 · 1998
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Plasma concentration and cardiovascular effects of intramuscular medetomidine combined with three doses of the peripheral alpha2-antagonist MK-467 in dogs
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1979
Cardiopulmonary and sedative effects of the peripheral α2-adrenoceptor antagonist MK 0467 administered intravenously or intramuscularly concurrently with medetomidine in dogs
10.2460/ajvr.73.5.587 · 2012
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Atipamezole increases medetomidine clearance in the dog: an agonist-antagonist interaction
10.1111/j.1365-2885.1995.tb00599.x · 1995
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10.1097/aap.0000000000000048 · doi-reference
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10.1111/vru.12305 · doi-reference
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10.1016/j.jvc.2024.04.003 · doi-reference
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10.1007/s12325-019-01101-6 · doi-reference
Effects of intramuscular vatinoxan (MK-467), co-administered with medetomidine and butorphanol, on cardiopulmonary and anaesthetic effects of intravenous ketamine in dogs
10.1016/j.vaa.2020.05.008 · doi-reference
Cardiovascular and sedation reversal effects of intramuscular administration of atipamezole in dogs treated with medetomidine hydrochloride with or without the peripheral α2-adrenoceptor antagonist vatinoxan hydrochloride
10.2460/ajvr.80.10.912 · doi-reference
Effects of MK-467 hydrochloride and hyoscine butylbromide on cardiorespiratory and gastrointestinal changes induced by detomidine hydrochloride in horses
10.2460/ajvr.79.4.376 · doi-reference
Effects of acepromazine and dexmedetomidine, followed by propofol induction and maintenance with isoflurane anaesthesia, on the microcirculation of Beagle dogs evaluated by sidestream dark field imaging: an experimental trial
10.1016/j.vaa.2022.04.001 · doi-reference
Pharmacokinetics and analgesic effects of intravenous, intramuscular or subcutaneous buprenorphine in dogs undergoing ovariohysterectomy: a randomized, prospective, masked, clinical trial
10.1186/s12917-020-02364-w · doi-reference
Propofol anesthesia
10.1016/s0195-5616(99)50059-4 · doi-reference