Peptide Therapeutics 2.0
10.3390/molecules25102293 · 2020
Trends in peptide drug discovery
10.1038/s41573-020-00135-8 · 2021
Peptide-based therapeutics: challenges and solutions
10.1007/s00044-024-03269-1 · 2024
Recent developments in the reduction of aromatic and aliphatic nitro compounds to amines
10.1021/acs.oprd.6b00205 · 2018
Selective hydrogenation for fine chemicals: recent trends and new developments
10.1002/adsc.200390000 · 2003
Catalytic static mixer-enabled hydrogenation of a key fenebrutinib intermediate: real-time analysis for a stable and scalable process
10.1021/acs.oprd.1c00258 · 2021
Catalytic transfer hydrogenation
10.1021/cr60291a003 · 1974
Ten key issues in modern flow chemistry
10.1039/c0cc05060a · 2011
The hitchhiker’s guide to flow chemistry
10.1021/acs.chemrev.7b00183 · 2017
Fixed bed continuous hydrogenations in trickle flow mode: A pharmaceutical industry perspective
10.1021/acs.oprd.2c00034 · 2022
Recent progress in continuous-flow hydrogenation
10.1002/cssc.202000778 · 2020
Process intensification for the continuous flow hydrogenation of ethyl nicotinate
10.1021/op500208j · 2014
Heterogeneous catalytic hydrogenation reactions in continuous-flow reactors
10.1002/cssc.201000354 · 2011
Membrane reactor based on hybrid nanomaterials for process intensification of catalytic hydrogenation reaction: an example of reduction of the environmental footprint of chemical synthesis from a batch to a continuous flow chemistry process
10.3303/cet1647062 · 2016
The expanding utility of continuous flow hydrogenation
10.1039/c5ob01067e · 2015
Improved continuous flow processing: benzimidazole ring formation via catalytic hydrogenation of an aromatic nitro compound
10.1021/op400179f · 2014
Recent developments in the use of flow hydrogenation in the field of medicinal chemistry
10.5772/65518 · 2017
Hydrogenation of nitroarenes in continuous flow with TPP/Raney Ni
10.1007/s41981-021-00156-3 · 2021
Synthesis of a crizotinib intermediate via highly efficient catalytic hydrogenation in continuous flow
10.1021/acs.oprd.0c00302 · 2020
Catalytic hydrogenation of N-4-nitrophenyl nicotinamide in a micro-packed bed reactor
10.1039/c7gc03469e · 2018
Fast gas–liquid–solid reactions in monoliths: A case study of nitro-aromatic hydrogenation
10.1016/j.cattod.2005.06.028 · 2005
Gas-liquid hydrogenation in continuous flow–The effect of mass transfer and residence time in powder packed-bed and catalyst-coated reactors
10.1016/j.cej.2019.122292 · 2020
Modeling and Simulation of the Hydrogenation of α-Methylstyrene on Catalytically Active Metal Foams as Tubular Reactor Packing
10.1155/2016/7082381 · 2016
Evaluation of reactor concepts for the continuous production of fine chemicals using the selective hydrogenation of cinnamaldehyde over palladium catalysts
10.1016/j.cattod.2013.12.051 · 2015
Structuring hybrid palladium nanoparticles in metallic monolithic reactors for continuous-flow three-phase alkyne hydrogenation
10.1039/c6re00114a · 2016
Using PAT to understand, control, and rapidly scale up the production of a hydrogenation reaction and isolation of pharmaceutical intermediate
10.1021/op500285x · 2015
In situ monitoring of catalytic three-phase enantioselective hydrogenation using FTIR/ATR spectroscopy
10.1016/j.apcata.2003.12.019 · 2004
Catalytic three-phase diastereoselective hydrogenation of o-toluic and 2-methyl nicotinic acid derivatives: In situ FTIR/ATR investigation
10.1016/j.vibspec.2007.04.003 · 2007
Process analytical technology (PAT): applications to flow processes for active pharmaceutical ingredient (API) development
10.1039/d2re00004k · 2022
Amide bonds meet flow chemistry: a journey into methodologies and sustainable evolution
10.1002/cssc.202102708 · 2022
Recent advances in the solid-and solution-phase synthesis of peptides and proteins using microflow technology
10.1021/acs.oprd.2c00074 · 2022
A fully automated flow-based approach for accelerated peptide synthesis
10.1038/nchembio.2318 · 2017
Deep learning for prediction and optimization of fast-flow peptide synthesis
10.1021/acscentsci.0c00979 · 2020
Evaluation of sponge metal catalysts in a trickle bed reactor for the continuous hydrogenation of an aliphatic nitro intermediate
10.1021/acs.oprd.9b00447 · 2020
Run Parameters for a Continuous Hydrogenation Process Using ACMC-Pd To Replace Commercial Batch Reactor Processes
10.1021/acs.oprd.8b00286 · 2018
Hydrogenation of aromatic nitrogroups with precious metal powder catalysts: influence of modifier on selectivity and activity
10.1007/s11244-010-9545-1 · 2010
Studying the Three-Phase Hydrogenation of Nitrobenzene to Aniline in the Presense of a Ruthenium Catalyst
10.1134/s2070050418040049 · 2018
Liquid phase hydrogenation of nitrobenzene
10.1016/j.apcata.2015.04.002 · 2015
Site-selective thiolation of (multi) halogenated heteroarenes
10.1021/jacs.0c01630 · 2020
Dual transition metal electrocatalysis: direct decarboxylative alkenylation of aliphatic carboxylic acids
10.1021/jacs.3c08839 · 2023
