Subcellular targeting strategies for drug design and delivery
10.1038/nrd2897 · doi-reference
Plausible mechanisms of Niclosamide as an antiviral agent against COVID-19
10.1016/j.mehy.2020.109765 · doi-reference
Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential
10.1021/acsinfecdis.0c00052 · doi-reference
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
10.1038/nm.4184 · doi-reference
Multi-targeted therapy of cancer by niclosamide: A new application for an old drug
10.1016/j.canlet.2014.04.003 · doi-reference
Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer
10.1038/s41419-017-0092-6 · doi-reference
Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers
10.1038/s41467-018-05805-1 · doi-reference
Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling
10.1074/jbc.m112.359638 · doi-reference
Mechanism of Action of Reagents that uncouple Oxidative Phosphorylation
10.1038/2211016a0 · doi-reference
Small Molecule Mitochondrial Uncouplers and Their Therapeutic Potential
10.1021/acs.jmedchem.7b01182 · doi-reference
Overcoming Drug Resistance by Targeting Cancer Bioenergetics with an Activatable Prodrug
10.1016/j.chempr.2018.08.002 · doi-reference
Mitochondrial Relocation of a Common Synthetic Antibiotic: A Non-genotoxic Approach to Cancer Therapy
10.1016/j.chempr.2020.03.004 · doi-reference
A Systematic Study of Coumarin–Tetrazine Light-Up Probes for Bioorthogonal Fluorescence Imaging
10.1002/chem.202001290 · doi-reference
Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications
10.1021/acs.chemrev.7b00042 · doi-reference
Transition-Metal-Mediated versus Tetrazine-Triggered Bioorthogonal Release Reactions: Direct Comparison and Combinations Thereof
10.1002/cplu.202000477 · doi-reference
Unraveling Tetrazine-Triggered Bioorthogonal Elimination Enables Chemical Tools for Ultrafast Release and Universal Cleavage
10.1021/jacs.7b11217 · doi-reference
Bioorthogonal Tetrazine Carbamate Cleavage by Highly Reactive trans-Cyclooctene
10.1021/jacs.0c00531 · doi-reference
Triggered Drug Release from an Antibody-Drug Conjugate Using Fast “Click-to-Release” Chemistry in Mice
10.1021/acs.bioconjchem.6b00231 · doi-reference
Chemical Control over T-Cell Activation in Vivo Using Deprotection of trans-Cyclooctene-Modified Epitopes
10.1021/acschembio.8b00155 · doi-reference
Controlled in-cell activation of RNA therapeutics using bond-cleaving bio-orthogonal chemistry
10.1039/c7sc01380a · doi-reference
Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice
10.1038/s41467-018-03880-y · doi-reference
Bioorthogonal tetrazine-mediated transfer reactions facilitate reaction turnover in nucleic acid-templated detection of microRNA
10.1021/ja510839r · doi-reference
In Vivo Bioorthogonal Chemistry Enables Local Hydrogel and Systemic Pro-Drug To Treat Soft Tissue Sarcoma
10.1021/acscentsci.6b00150 · doi-reference
Bio-Orthogonal Chemistry and Reloadable Biomaterial Enable Local Activation of Antibiotic Prodrugs and Enhance Treatments against Staphylococcus aureus Infections
10.1021/acscentsci.8b00344 · doi-reference
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells
10.1002/anie.201609607 · doi-reference
The Emerging Role of Tetrazines in Drug-Activation Chemistries
10.1002/cbic.201800590 · doi-reference
Click-to-Release from trans-Cyclooctenes: Mechanistic Insights and Expansion of Scope from Established Carbamate to Remarkable Ether Cleavage
10.1002/anie.201800402 · doi-reference
