Age-associated loss of lamin-B leads to systemic inflammation and gut hyperplasia
10.1016/j.cell.2014.10.028 · doi-reference
Age-dependent Lamin changes induce cardiac dysfunction via dysregulation of cardiac transcriptional programs
10.1038/s43587-022-00323-8 · doi-reference
Nuclear envelope rupture and NET formation is driven by PKCα-mediated lamin B disassembly
10.15252/embr.201948779 · doi-reference
Chromatin swelling drives neutrophil extracellular trap release
10.1038/s41467-018-06263-5 · doi-reference
Cellular mechanisms of NETosis
10.1146/annurev-cellbio-020520-111016 · doi-reference
Loss of lamin-B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus
10.1111/acel.13521 · doi-reference
Lamin B1 decline underlies age-related loss of adult hippocampal neurogenesis
10.15252/embj.2020105819 · doi-reference
Declining lamin B1 expression mediates age-dependent decreases of hippocampal stem cell activity
10.1016/j.stem.2021.01.015 · doi-reference
Tau oligomerization induces nuclear lamina invagination and chromatin remodeling in Alzheimer’s disease
10.1007/s00401-026-03018-1 · doi-reference
Pathological α-synuclein perturbs nuclear integrity
10.1016/j.nbd.2025.107028 · doi-reference
Neuronal α-synuclein toxicity is the key driver of neurodegeneration in multiple system atrophy
10.1093/brain/awaf030 · doi-reference
Protein aggregation and neurodegenerative disease
10.1038/nm1066 · doi-reference
Tau modulates nuclear integrity, chromatin, and cholesterol synthesis genes via the nuclear envelope
10.64898/2025.12.05.692577 · doi-reference
Disruption of nuclear envelope integrity as a possible initiating event in tauopathies
10.1016/j.celrep.2022.111249 · doi-reference
Cell confinement initiates a delayed but heritable loss of chromosomes
10.1016/j.celrep.2026.117053 · doi-reference
Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environments
10.1007/s12195-014-0342-y · doi-reference
Nuclear envelope composition determines the ability of neutrophil-type cells to passage through micron-scale constrictions
10.1074/jbc.m112.441535 · doi-reference
Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival
10.1083/jcb.201308029 · doi-reference
Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging
10.1161/atvbaha.110.209460 · doi-reference
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
10.1038/nature01629 · doi-reference
Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity
10.1186/s12967-023-04542-4 · doi-reference
Doubly heterozygous LMNA and TTN mutations revealed by exome sequencing in a severe form of dilated cardiomyopathy
10.1038/ejhg.2013.16 · doi-reference
Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease
10.1056/nejm199912023412302 · doi-reference
Primordial germ cells experience increasing physical confinement and DNA damage during migration in the mouse embryo
10.1126/sciadv.aec7919 · doi-reference
Lem2 is essential for cardiac development by maintaining nuclear integrity
10.1093/cvr/cvad061 · doi-reference
Scaling laws indicate distinct nucleation mechanisms of holes in the nuclear lamina
10.1038/s41567-019-0506-8 · doi-reference
Mechanisms of A-type Lamin targeting to nuclear ruptures are disrupted in LMNA- and BANF1-associated progerias
10.3390/cells11050865 · doi-reference
The NSL complex maintains nuclear architecture stability via lamin A/C acetylation
10.1038/s41556-019-0397-z · doi-reference
Parvoviruses cause nuclear envelope breakdown by activating key enzymes of mitosis
10.1371/journal.ppat.1003671 · doi-reference
The very-long-chain fatty acid elongase Elo2 rescues lethal defects associated with loss of the nuclear barrier function in fission yeast cells
10.1242/jcs.229021 · doi-reference
Disordered region of nuclear membrane protein Bqt4 recruits phosphatidic acid to the nuclear envelope to maintain its structural integrity
10.1016/j.jbc.2024.107430 · doi-reference
Direct binding of ESCRT protein Chm7 to phosphatidic acid-rich membranes at nuclear envelope herniations
10.1083/jcb.202004222 · doi-reference
Components of an ESCRT-independent nuclear envelope assembly pathway
10.64898/2026.02.01.703137 · doi-reference
Factors promoting nuclear envelope assembly independent of the canonical ESCRT pathway
10.1083/jcb.201908232 · doi-reference
DNA-induced liquid phase condensation of cGAS activates innate immune signaling
10.1126/science.aat1022 · doi-reference
A protein-DNA surface hydrogel mechanically reinforces the cell nucleus and protects the genome
10.1101/2025.05.21.655270 · doi-reference
LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation
10.1038/s41586-020-2232-x · doi-reference
DNA cross-bridging shapes a single nucleus from a set of mitotic chromosomes
10.1016/j.cell.2017.07.038 · doi-reference
Barrier-to-autointegration factor (BAF) bridges DNA in a discrete, higher-order nucleoprotein complex
10.1073/pnas.150240197 · doi-reference
Mitosis sets nuclear homeostasis of cancer cells under confinement
10.7554/elife.94975.1 · doi-reference
