Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies
10.1016/s0140-6736(74)90140-8 · 1974
High carbohydrate diets and insulin efficiency
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Diabetes mellitus. Its differentiation into insulin-sensitive and insulin-insensitive types
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The molecular and physiological basis of insulin resistance: emerging implications for metabolic and cardiovascular disease
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Plasma insulin response to sustained hyperglycaemia induced by glucose infusion in human subjects
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The plasma insulin response to glucose infusion in healthy subjects and in diabetes mellitus
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Glucose tolerance and serum insulin in unaffected identical twins of diabetics
10.1136/bmj.4.5570.21 · 1967
Insulin secretion in response to glycemic stimulus: relation of delayed initial release to carbohydrate intolerance in mild diabetes mellitus
10.1172/jci105534 · 1967
Diminished serum insulin response to glucose in genetic prediabetic males with normal glucose tolerance
10.2337/diab.17.1.17 · 1968
Insulin deficiency and insulin resistance in the pathogenesis of type 2 diabetes: is a divorce possible?
10.1007/bf00400591 · 1995
Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes
10.1016/s0092-8674(00)80546-2 · 1999
Interactions between insulin resistance and insulin secretion in the development of glucose intolerance
10.1172/jci10761 · 2000
Effect of 6-month gliclazide treatment on insulin release and sensitivity to endogenous insulin in NIDDM: role of initial continuous subcutaneous insulin infusion-induced normoglycemia
10.1016/0002-9343(91)90416-u · 1991
Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment
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The response to short-term intensive insulin therapy in type 2 diabetes
10.1111/j.1463-1326.2009.01129.x · 2010
Effect of intensive insulin therapy on ß-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: A multicentre randomised parallel-group trial
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Studies on low insulin responders
10.1530/acta.0.090s005 · 1979
Relationship between the plasma insulin response to oral glucose and insulin-stimulated glucose utilization in normal subjects
10.2337/diabetes.33.5.460 · 1984
Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians
10.1056/nejm199312303292703 · 1993
Insulin resistance and hypersecretion in obesity
10.1172/jci119628 · 1997
Dose-response relationship of plasma insulin and blood glucose levels during oral glucose loads in prediabetic and diabetic subjects
10.1016/s0140-6736(73)90599-0 · 1973
The pathogenesis of NIDDM
10.1007/bf00400840 · 1994
β-cell function in subjects spanning the range from normal glucose tolerance to overt diabetes: a new analysis
10.1210/jc.2004-1133 · 2005
Relationships between fasting plasma glucose levels and insulin secretion during intravenous glucose tolerance tests
10.1210/jcem-42-2-222 · 1976
Pulsatile insulin secretion: detection, regulation, and role in diabetes
10.2337/diabetes.51.2007.s245 · 2002
GIP and GLP-1, the two incretin hormones: similarities and differences
10.1111/j.2040-1124.2010.00022.x · 2010
K-value and low insulin secretion in a non-obese white population predicted glucose tolerance after 25 years
10.1007/s00125-005-1929-6 · 2005
Oral disposition index predicts the development of future diabetes above and beyond fasting and 2-h glucose levels
10.2337/dc08-1478 · 2009
Primary defects in β-cell function further exacerbated by worsening of insulin resistance mark the development of impaired glucose tolerance in obese adolescents
10.2337/dc08-1274 · 2009
Insulin response to glucose infusion in diabetic and non-diabetic monozygotic twin pairs. Genetic control of insulin response?
10.1530/acta.0.0550330 · 1967
Glucose tolerance and serum insulin in identical twins of diabetics
10.1136/bmj.4.5736.649 · 1970
Genetic regulation of the kinetics of glucose-induced insulin release in man - studies in families with diabetic and non-diabetic probands
10.1111/j.1399-0004.1985.tb01210.x · 1985
Genetic influences on the insulin response of the beta cell to different secretagogues
10.1007/s00125-009-1532-3 · 2009
Pathomechanisms of type 2 diabetes genes
10.1210/er.2009-0017 · 2009
Beta cell glucose sensitivity is decreased by 39% in non-diabetic subjects carrying multiple diabetes-risk alleles compared with those with no risk alleles
10.1007/s00125-008-1124-7 · 2008
Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycaemic clamps
10.2337/db09-0736 · 2010
Type 2 diabetes susceptibility gene TCF7L2 and its role in β-cell function
10.2337/db09-0099 · 2009
TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells
10.2337/db08-1187 · 2009
Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP and GLP-1 receptors and impaired beta-cell function
10.1093/hmg/ddp178 · 2009
Genotype and tissue-specific effects on alternative splicing of the transcription factor 7-like 2 gene in humans
10.1210/jc.2009-2064 · 2010
