Targeting calcium regulation for heart failure and arrhythmia therapeutics: a critical review
10.1161/circulationaha.125.075150 · doi-reference
From the laboratory to the clinic: differentiation, disease modeling and transplantation of cardiac organoids
10.1002/adhm.202502698 · doi-reference
Bridging the translational gap in heart failure research: using human iPSC-derived cardiomyocytes to accelerate therapeutic insights
10.14797/mdcvj.1295 · doi-reference
Small and large animal models in cardiac contraction research: advantages and disadvantages
10.1016/j.pharmthera.2013.10.007 · doi-reference
Safety, pharmacokinetics, and antiviral activity of the cyclophilin inhibitor NIM811 alone or in combination with pegylated interferon in HCV-infected patients receiving 14 days of therapy
10.1016/j.antiviral.2011.01.003 · doi-reference
Protective effects of cyclosporine and its analog NIM-811 in a murine model of hepatic ischemia-reperfusion injury
10.1016/j.livres.2024.02.002 · doi-reference
NIM811, A cyclophilin inhibitor without immunosuppressive activity, is beneficial in collagen VI congenital muscular dystrophy models
10.1093/hmg/ddu254 · doi-reference
Cyclosporine before PCI in patients with acute myocardial infarction
10.1056/nejmoa1505489 · doi-reference
Effect of cyclosporine on reperfusion injury in acute myocardial infarction
10.1056/nejmoa071142 · doi-reference
Mitochondrial permeability transition pore opening as an endpoint to initiate cell death and as a putative target for cardioprotection
10.1159/000103747 · doi-reference
What is the nature of the mitochondrial permeability transition pore and what is it not?
10.1002/iub.1130 · doi-reference
The permeability transition pore as a ca(2+) release channel: new answers to an old question
10.1016/j.ceca.2012.03.004 · doi-reference
Mitochondrial dysfunction in pathophysiology of heart failure
10.1172/jci120849 · doi-reference
Permeability transition in human mitochondria persists in the absence of peripheral stalk subunits of ATP synthase
10.1073/pnas.1711201114 · doi-reference
Dimers of mitochondrial ATP synthase form the permeability transition pore
10.1073/pnas.1217823110 · doi-reference
What is the mitochondrial permeability transition pore?
10.1016/j.yjmcc.2009.02.021 · doi-reference
Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions
10.1038/s41418-023-01187-0 · doi-reference
Mitochondrial calcium regulation of cardiac metabolism in health and disease
10.1152/physiol.00014.2024 · doi-reference
Mitochondrial calcium signaling and redox homeostasis in cardiac health and disease
10.3389/fmmed.2023.1235188 · doi-reference
Spatial and functional crosstalk between the mitochondrial na(+)-ca(2+) exchanger NCLX and the sarcoplasmic reticulum ca(2+) pump SERCA in cardiomyocytes
10.3390/ijms23147948 · doi-reference
Physiological and pathophysiological roles of mitochondrial na(+)-ca(2+) exchanger, NCLX, in hearts
10.3390/biom11121876 · doi-reference
MICU1 And MICU2 control mitochondrial calcium signaling in the mammalian heart
10.1073/pnas.2402491121 · doi-reference
How the mitochondrial calcium uniporter complex (MCU(cx)) works
10.1073/pnas.2015886117 · doi-reference
A calcium guard in the outer membrane: is VDAC a regulated gatekeeper of mitochondrial calcium uptake?
10.3390/ijms22020946 · doi-reference
Individual cardiac mitochondria undergo rare transient permeability transition pore openings
10.1161/circresaha.115.308093 · doi-reference
Pharmacology of mitochondrial permeability transition pore inhibitors
10.1002/ddr.21593 · doi-reference
Cardiac contractility modulation electrical signals normalize activity, expression, and phosphorylation of the na+-Ca2+ exchanger in heart failure
10.1016/j.cardfail.2008.08.011 · doi-reference
Ca2+ entry mode of na+/Ca2+ exchanger as a new therapeutic target for heart failure with preserved ejection fraction
10.1093/eurheartj/ehr106 · doi-reference
Alternative strategies in arrhythmia therapy: evaluation of na/ca exchange as an anti-arrhythmic target
10.1016/j.pharmthera.2011.12.001 · doi-reference
Acute inhibition of the na(+)/ca(2+) exchanger reduces proarrhythmia in an experimental model of chronic heart failure
10.1016/j.hrthm.2011.11.004 · doi-reference
Na(+)–Ca2+ exchange in the regulation of cardiac excitation-contraction coupling
10.1016/j.cardiores.2005.04.031 · doi-reference
Altered na+/ca2+-exchanger activity due to downregulation of na+/k+-ATPase alpha2-isoform in heart failure
10.1093/cvr/cvn013 · doi-reference
The na+/Ca2+ exchanger in cardiac ischemia/reperfusion injury
10.12659/msm.883533 · doi-reference
Mapping the in vitro interactome of cardiac sodium (na(+) )-calcium (ca(2+) ) exchanger 1 (NCX1)
10.1002/pmic.201600417 · doi-reference
Cardiac function is regulated by the sodium-dependent inhibition of the sodium-calcium exchanger NCX1
10.1038/s41467-024-47850-z · doi-reference
Triple threat: the na+/Ca2+ exchanger in the pathophysiology of cardiac arrhythmia, ischemia and heart failure
10.2174/138945011795378559 · doi-reference
Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport
10.1042/bj20070619 · doi-reference
Levosimendan: molecular mechanisms and clinical implications: consensus of experts on the mechanisms of action of levosimendan
10.1016/j.ijcard.2011.07.022 · doi-reference
Human cardiac troponin complex. Structure and functions
10.1134/s0006297913130063 · doi-reference
Tri-modal regulation of cardiac muscle relaxation; intracellular calcium decline, thin filament deactivation, and cross-bridge cycling kinetics
10.1007/s12551-014-0143-5 · doi-reference
