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Mutant KRAS-activated circATXN7 fosters tumor immunoescape by sensitizing tumor-specific T cells to activation-induced cell death
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ACAT1-Mediated ME2 acetylation drives chemoresistance in ovarian cancer by linking glutaminolysis to lactate production
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Lactylation in health and disease: physiological or pathological?
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Histone lactylation bridges metabolic reprogramming and epigenetic rewiring in driving carcinogenesis: oncometabolite fuels oncogenic transcription
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A rising star involved in tumour immunity: lactylation
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The role of glycolysis and lactate in the induction of tumor-associated macrophages immunosuppressive phenotype
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Royal jelly acid suppresses hepatocellular carcinoma tumorigenicity by inhibiting H3 histone lactylation at H3K9la and H3K14la sites
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Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells
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KAT8-catalyzed lactylation promotes eEF1A2-mediated protein synthesis and colorectal carcinogenesis
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CircXRN2 suppresses tumor progression driven by histone lactylation through activating the Hippo pathway in human bladder cancer
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A phase II study of the orally administered negative enantiomer of gossypol (AT-101), a BH3 mimetic, in patients with advanced adrenal cortical carcinoma
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Interplay between metabolic reprogramming and post-translational modifications: from glycolysis to lactylation
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The emerging era of lactate: a rising star in cellular signaling and its regulatory mechanisms
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Microbiotic nanomedicine for tumor-specific chemotherapy-synergized innate/adaptive antitumor immunity
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Lactate dehydrogenases amplify reactive oxygen species in cancer cells in response to oxidative stimuli
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Metabolite transporters as regulators of immunity
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Dendritic cells in cancer immunology and immunotherapy
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Lactate-induced protein lactylation in cancer: functions, biomarkers and immunotherapy strategies
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Ubiquitous protein lactylation in health and diseases
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The relationship and clinical significance of lactylation modification in digestive system tumors
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Comprehensive multiscale analysis of lactate metabolic dynamics in vitro and in vivo using highly responsive biosensors
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Lactate-induced protein lactylation: a bridge between epigenetics and metabolic reprogramming in cancer
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Lactate in the tumour microenvironment: from immune modulation to therapy
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Lactic acid and an acidic tumor microenvironment suppress anticancer immunity
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Lactylation and human disease
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Cyclic immonium ion of lactyllysine reveals widespread lactylation in the human proteome
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