Institutional research

All affiliated publications

57 works connected to Fundação Oswaldo Cruz.

Evaluation of antitrichomonal activity of coffeewaste compounds against different Trichomonas vaginalis strains: An in vitro and in silico study

Microbial Pathogenesis · 2026 · journal-article

Laura Gonçalves Rezende, Wanderleya Toledo dos Santos, Anna De Freitas, Fernanda Maria Pinto Vilela, Victor do Valle Pereira Midlej, Humberto Moreira Húngaro, Ana Claudia Chagas de Paula, Vinícius Gonçalves Maltarollo, Lauren Hubert Jaeger

Quinoline-aminothiophenol derivative triggers pronounced mitochondrial dysfunction and cell death in Leishmania infantum

Chemico-Biological Interactions · 2026 · journal-article

Stephane França Ribeiro, Wander Luiz Alves Amorim, Bruno Vicente, Victor do Valle Pereira Midlej, Adolfo Firmino da Silva Neto, Nícolas Glanzmann, Juciane Maria de Andrade Castro, Maria Luiza Pereira Baltazar, Priscila Vanessa Zabala Capriles Goliatt, Adilson David da Silva, Elaine Soares Coimbra, Luciana Maria Ribeiro Antinarelli

A systematic review and individual patient data meta-analysis to determine the effect of primaquine dose on efficacy, tolerability and safety in uncomplicated Plasmodium vivax malaria in Latin America

The Lancet Regional Health - Americas · 2026 · journal-article

Kathy Nguyen, Anielle de Pina-Costa, Megha Rajasekhar, Nathália N. Chamma-Siqueira, André Daher, Marcelo U. Ferreira, Margarete do Socorro M. Gomes, Lilia González-Cerón, Justin A. Green, Gavin Koh, Simone Ladeia-Andrade, Alejandro Llanos-Cuentas, Wuelton Marcelo Monteiro, Suaine C. Negreiros, Alexandre Macedo de Oliveira, Dhelio B. Pereira, Giselle M.R. Viana, J.L.F. Vieira, Lina Zuluaga-Idárraga, Hyaa Hoseen M. Alatawi, Philippe J. Guerin, Julie A. Simpson, Marcus Lacerda, Ric N. Price, Andre M. Siqueira, Robert J. Commons

Discovery of natural product antagonists for the P2X7 receptor through virtual screening

Biomedicine & Pharmacotherapy · 2026 · journal-article

Natiele Carla da Silva Ferreira, Lauro Miranda Lima, Nicole de Menezes Macedo, Esther dos Santos Campos, Anael Viana Pinto Alberto, Lucas Gasparello Viviani, Antonia Tavares do Amaral, Luiz Anastácio Alves

Entre a adolescência e a invisibilidade: representações sociais da juventude e o direito à saúde no Brasil

2026 · posted-content

André Luiz Da Silva Sobrinho, Helena Abramo, Bianca Borges da Silva Leandro, Luciane Cristina Ferrareto, Eric Veiga Andriolo, Mariana Lyra

Ultrastructural Analysis of Extracellular Vesicles and Surface Protrusions from the Parasite Tritrichomonas foetus

2026 · posted-content

Verónica M. Cóceres, Abigail Miranda-Magalhães, Regina Célia Bressan Queiroz de Figueiredo, Natalia de Miguel, Antonio Pereira‐Neves

Eco-phenotypic characterization of Candida palmioleophila from poultry litter and marine environments: implications for One Health

Archives of Microbiology · 2026 · journal-article

Dario Corrêa-Junior, Igor Avellar-Moura, Marcos de Abreu Almeida, Elisa Gonçalves Medeiros, Alessandro Fernandes Valdez, Rodrigo Almeida-Paes, Leonardo Nimrichter, Cláudio Ernesto Taveira Parente, Allan Jefferson Guimaraes, Susana Frasés

Movimentos sociais como arenas de coexistência geracional: uma proposta analítica

2026 · posted-content

André Luiz Da Silva Sobrinho

AutoHMD: Scalable and Accurate Validation of Antibody–Antigen Complexes by Heated Molecular Dynamics

Bioinformatics · 2026 · journal-article

Julia S Souza, Aline O. Albuquerque, Diego S Almeida, Andrielly H S Costa, Jean V Sampaio, João H M Silva

Evaluating periportal fibrosis in schistosomiasis mansoni using the ELF [Enhanced Liver Fibrosis] score: A pilot study

PLOS Neglected Tropical Diseases · 2026 · journal-article

Rebecca Dantas Thorp, Andrea Dória Batista, Carolline Araujo, Lilian Rose Maia Gomes de Araújo, George Tadeu Nunes Diniz, ANA VIRGÍNIA MATOS SÁ BARRETO, Clarice Neueschwander Lins Morais, Paula Carolina Valença Silva, Ana Lúcia Coutinho Domingues

Molecular remodelling of Cryptococcus neoformans during adaptation to host temperature

Journal of Medical Microbiology · 2026 · journal-article

Marianna Dallastella, Isadora F. Munhoz da Rocha, Bruno A. A. Romagnoli, Lysangela R. Alves

Evaluation of a multiplex qPCR assay for rapid diagnosis of fungal pneumonia and tuberculosis in people with advanced HIV disease

Medical Mycology · 2026 · journal-article

Thiago Brasil de Moura da Costa, Pedro Henrique Nascimento Theodoro, José Henrique de Melo Neto, Fernando Almeida-Silva, Maria Cristina Lourenço, Rodrigo Almeida-Paes, Andrea d'Ávila Freitas, Valdiléa G Veloso, Sandra Wagner Cardoso, Maria José Buitrago, Marcel de Souza Borges Quintana, Freddy Perez, Rosely Maria Zancopé-Oliveira

Parasitological and molecular characterization of gastrointestinal parasites in free-ranging capybaras (Hydrochoerus hydrochaeris) from urbanized environments in Rio de Janeiro, Brazil

Veterinary Parasitology: Regional Studies and Reports · 2026 · journal-article

Fabiana Valadão Massad, Daphnne Chelles Marins, Isadora de Fátima Braga Magalhães, Marcos Pereira da Silva Junior, Beatriz Pinheiro Melo da Silva, Eric Vinicius Rezende Bispo, Jefferson Pereira Caldas dos Santos, Gabrielle Fontenelle, Thomas Salles Dias, Cláudio Alessandro Massamitsu Sakamoto, Luciano Antunes Barros, Cátia Dejuste de Paula, Nathalie Costa da Cunha

Capybara Oil‐Based Nanoemulsion Attenuates Obesity‐Induced Renal Injury Through Modulation of Inflammation, Oxidative Stress, and Fibrosis in Mice

Cell Biochemistry and Function · 2026 · journal-article

Priscila Gomes Pereira, Luciana Lontro Alves, Bianca Torres Ciambarella, Stela Regina Ferrarini, Ana Lucia R. Nascimento, Cherley Borba Vieira de Andrade, Alan César Nunes de Moraes, Andressa Bernardi, Fernanda Verdini Guimarães, Miguel Porto Campos, D. M. S. Valladão, Letícia Cruz, Jemima Fuentes Ribeiro da Silva, Kíssila Rabelo, Jorge José de Carvalho

Baseline fluconazole heteroresistance and risk of relapse within six months among patients with neurocryptococcosis in the Brazilian Amazon

Medical Mycology · 2026 · journal-article

Izabela de Mesquita Bárcia Moreira, Ingrid Bianca Silva, João Flavio Dias do Val Bisneto, NAIRA SULANY OLIVEIRA DE SOUSA, Juan Diego Ribeiro de Almeida, Robert Langlady Lira Rosas Filho, Nayara de Fátima Lazameth-Diniz, Kátia Santana Cruz, Carla Silvana da Silva Santos, Ani Beatriz Jackisch Matsuura, Érica Simplício de Souza, Marcia de Souza Carvalho Melhem, Hagen Frickmann, João Vicente Braga de Souza

Discovery of Novel Peptides as DPP-IV Inhibitors: In Silico Screening, Molecular Dynamics Simulations, and Preliminary In Vitro Evaluation

ACS Omega · 2026 · journal-article

Burak ÇALIŞ, Fernando Berton Zanchi, Beyza Canakcimaksutoglu, Ahmet E. Yetiman, Özkan Fidan

Horizontal mitochondrial transfer and mitochondrial transplantation in skin: protection against UVR-induced ROS damage and enhancement of cell proliferation and wound healing

Journal of Translational Medicine · 2026 · journal-article

Andrés Caicedo, Abigail Benavides-Almeida, Sebastian Peñaherrera, Paola Robayo, A. Villagomez, Matheo Leon, Andrés Suárez‐Usbeck, Santiago D. Padilla-Sánchez, Martin Santacruz, Tatiana Borja, María Belén Arteaga, Alissen Haro-Vinueza, Gilberto Segnini, P. Pontón, Fernando Torres, Gustavo Donoso, Daniela Suquillo, Lucas Ferreira dos Santos, Pamela Arizo, D. Tenesaca, Bárbara Antilef, Gabriela Zavala, Diego Barba, Luciano Ferrada, Andrea Del Campo, Kevin Zambrano, Sebastián Chile-Miranda, Cynthia Viera-Catota, Solange Cisterna, D. Villavicencio, Álvaro A. Pérez-Meza, Diego F. Cisneros-Heredia, Pedro M. Aponte, Francisco Cabrera, Patricia Luz‐Crawford, Iván M. Moya, María Ines Mitrani, Maroun Khoury, Estefanía Nova-Lamperti, Verónica A. Burzio, Tatiana Maron‐Gutierrez, Ramiro F. Diaz

Floral dynamics in the protandrous flowers of Bauhinia variegata (Fabaceae): phase-specific morphology, scent, and nectar production

Planta · 2026 · journal-article

Andrews Vinicius Santos da Silva, VIDAL FREITAS MANSANO, Dalton Guimarães Veloso, Ana Cláudia F. Amaral, Jefferson D. da Cruz, Fabrício de Oliveira Silva, Walter Sotto Mayor Fernandes Neto, Jefferson Rocha de Andrade Silva, Pedro Joaquim Bergamo, Leandro Freitas, Juliana Villela Paulino

Detection of Rickettsia spp. in Ticks from Domestic Dogs Living in Seven Major Indigenous Communities of Rio de Janeiro State, Brazil

Pathogens · 2026 · journal-article

Amanda Scardini Leon Isaac, Tiago Marques dos Santos, Gabriel Batista da Silva Leão, Thaís Silva Oliveira, MARIA ANGÉLICA DA SILVA FERREIRA, Cheryl Gouveia, Thainá Aparecida Pereira Moura Cerqueira, Jhone Inácio Silveira, Leandro Meneguelli Biondo, Louise Bach Kmetiuk, Cláudia Bezerra da Silva, Bruna de Azevedo Baêta, Carla de Freitas Campos, Alexander Welker Biondo, Matheus Dias Cordeiro

Comprehensive Stability Assessment of Squalene in a Nanoemulsion Adjuvant and the SpiN-Tec Vaccine: HPLC Quantification, Stress Testing, and Stability Studies

AAPS PharmSciTech · 2026 · journal-article

Isabela Pereira Gomes, Graziella Gomes Rivelli, Flávia Fonseca Bagno, Natália Satchiko Hojo-Souza, Ana Luiza Chaves Maia, Liliane Martins dos Santos, Bruna Rodrigues Dias Assis, Natália Salazar de Castro, Wellington Vargas, Rafael Rodrigues de Barros, Natália Andrade de Freitas, Gisele Assis Castro Goulart, Renan Pedra de Souza, Santuza Maria Ribeiro Teixeira, Ana Paula Fernandes, Ricardo T. Gazzinelli, Eduardo Burgarelli Lages

Representações sociais de estudantes do ensino médio técnico integrado sobre experimentação animal

Investigações em Ensino de Ciências · 2026 · journal-article

Natalia Lopes de Carvalho, Gabriela Conceição de Souza, Mariana Conceicao de Souza, Etinete Nascimento Gonçalves

Real-world evaluation of the FluoroType MTBDR 2.0 assay for detection of rifampicin and isoniazid resistance-conferring mutations in Mycobacterium tuberculosis complex clinical isolates

Microbiology Spectrum · 2026 · journal-article

Fabiane Maria de Almeida Ferreira, Angela Pires Brandão, Thiago Brobio Massanti, Antonio Carlos da Silva Rego, Lucilaine Ferrazoli, Érica Chimara, Rosângela Siqueira de Oliveira (orientadora), Juliana Maíra Watanabe Pinhata

Burden of respiratory syncytial virus (RSV) hospitalizations among adults aged 60 years or more in Brazil: A retrospective surveillance database analysis (2013–2024)

PLOS One · 2026 · journal-article

Bruna Medeiros Gonçalves de Veras, Lessandra Michelin, Julio Croda, Thaís Zamboni Berra, Gustavo Pires-Matheus, Igor Sampietri, Magda Araújo, Rosemeri Maurici da Silva, Adriana Guzmán-Holst

Acute-phase biomarker correlation networks and myopericardial involvement on follow-up cardiac magnetic resonance imaging after COVID-19

Scientific Reports · 2026 · journal-article

Eric Henrique Roma, Andréa Silvestre-Sousa, Gabriel Camargo, Ana Teresa Fernandes, Fabielle Marques-Santos, Alinne Rangel dos Santos Renzetti, Emiliano Horacio Medei, Julia Machado Barroso, Ronir Raggio Luiz, Maria da Glória Bonecini-Almeida, Renata Junqueira Moll-Bernardes

Judicialização e direito à saúde no Brasil: repercussões jurídicas, econômicas e assistenciais

Aposta: Revista de Ciencias Sociales · 2026 · journal-article

Gabrielle Nepomuceno da Costa Santana, Fabiana Santos de Brito, Helen Santos, Aline Cristina Moura, Patrícia Lourdes Silva, Fábio Mello da Rosa, Maria do Socorro Macêdo Coêlho Lima, Kassiana Renê Gomes, Rafael Teixeira Sebastiani, Moisés Gonçalves Rodrigues, Pedro Victor Rodrigues Linhares

Free Phenolic Hydroxyl Groups Govern the Anticancer Activity of α‐Mangostin: A Structure–Activity Relationship Insight

ChemFoodChem · 2026 · journal-article

Otávio Augusto Chaves, Afonso Santine M. M. Velez, Lívia Stenico Tanajura, Douglas C. Alcântara Pinto, Débora Decotè-Ricardo, Eliézer Ávila Gandra, Marco Edílson Freire de Lima, Carlos Serpa

Multidisciplinary Team Perceptions on Preparing Newborns for Discharge From a Rooming‐in Unit: A Qualitative Study

Health Science Reports · 2026 · journal-article

Thaís Emanuele da Conceição, Adriana Duarte Rocha, Cristina Lumia, Simona Fumagalli, Antonella Nespoli, M de O Souza

Auricularia auricula’s Polysaccharides Confer Protection in Murine Sepsis via Immune Modulation

Journal of Immunology Research · 2026 · journal-article

Jesse Pereira Machado Viana, Luísa Coutinho Coelho, Priscila Mendonça Mendes, André Álvares Marques Vale, Jeferson Noslen Casarin, Joicy Cortez de Sá Sousa, Paulo Vitor Soeiro Pereira, Maria Carolina Bezerra Di Medeiros Leal, Anamélia Lorenzetti Bocca, Márcia Cristina Gonçalves Maciel

Epidemiology and social factors of malaria in the Yanomami Indigenous Territory: a critical review of the challenges of control and elimination

Memórias do Instituto Oswaldo Cruz · 2026 · journal-article

Djane Clarys Baía-da-Silva, Alexander Vargas, Edilia Sâmela Freitas Santos, Karolina Jeaneth Solórzano Chavarría, Cláudio Tadeu Daniel-Ribeiro, Wuelton Marcelo Monteiro

Sarcopenia, obesidade e limitações nas atividades diárias em pessoas idosas do Elsi-Brasil: recomendações do Sarcopenia Definition and Outcomes Consortium

Ciência & Saúde Coletiva · 2026 · journal-article

Ana Lúcia Danielewicz, Bruno Prates Freitas, Bruno de Souza Moreira, Elaine Cristina Lopes, Rafaela Aguiar Rosa, Maria Fernanda Lima-Costa, Núbia Carelli Pereira de Avelar

Morte materna por aborto nos estados da região Norte: uma análise de 2012 a 2022

Ciência & Saúde Coletiva · 2026 · journal-article

Gabriela Góes, L. C. T. Guillen, Carla Lourenço Tavares de Andrade, Marcos Augusto Bastos Dias

Evolution of dental procedures in Brazil: an analysis of the last cycles of PMAQ-AB

Ciência & Saúde Coletiva · 2026 · journal-article

Maria Tereza Abreu Scalzo, Mauro Henrique Nogueira Guimarães de Abreu, Juliana Vaz de Melo Mambrini, Suellen da Rocha Mendes, Antônio Thomaz Gonzaga da Matta Machado, Renata de Castro Martins

Acesso aos antipsicóticos no Brasil: usando a gestão de riscos para dimensionar mudanças na assistência farmacêutica

Ciência & Saúde Coletiva · 2026 · journal-article

Lucas Reis Felício, Cristina Mariano Ruas, Sarah Nascimento Silva

Distinct IRF6 dysfunction mechanisms in syndromic orofacial clefts: Computational evidence for allosteric versus direct disruption

Computational and Structural Biotechnology Journal · 2025 · journal-article

Ana Luiza Meneguci Moreira Franco, Deborah Antunes, Ana Clara Rodrigues Moreira Gomes, Bruno Dias, Henrique Pessoa Ladvocat Cintra, Ana Carolina Ramos Guimarães, Elizeu Fagundes de Carvalho, Fernando Regla Vargas, Flávia Martinez de Carvalho

Inference of essential genes in Brugia malayi and Onchocerca volvulus by machine learning and the implications for discovering new interventions

Computational and Structural Biotechnology Journal · 2024 · journal-article

Túlio de Lima Campos, Neil David Young, Bill C. H. Chang

Acute promyelocytic leukemia: the first reported case diagnosed by immunophenotyping in Mozambique

Discover Medicine · 2024 · journal-article

Edson Mongo, Felismina Matola, Adérito Sigaúque, Vânia Monteiro, Onélia Guiliche, Teresa Babetine, Lena Manhique-Coutinho, Juliana Ruth Mutchamua, Angelina Dias, Dadirayi Mutsaka, Tom Decroo, Tinne Gils, Chishamiso Mudenyanga, Faizana Amodo, Eugênia Terra‐Granado, Raquel Matavele Chissumba

In silico and in vivo analysis reveal impact of c-Myc tag in FMC63 scFv-CD19 protein interface and CAR-T cell efficacy

Computational and Structural Biotechnology Journal · 2024 · journal-article

Ana Julia Ferreira Lima, Karina Lôbo Hajdu, Luiza de Macedo Abdo, Leonardo Ribeiro Batista-Silva, Clara de Oliveira Andrade, Eduardo Mannarino Correia, Emmanuel Arthur Albuquerque Aragão, Martín Bonamino, Marcos Roberto Lourenzoni

Comprehensive analysis of early T cell responses to acute Zika Virus infection during the first epidemic in Bahia, Brazil

PLOS One · 2024 · journal-article

Assia Samri, Antonio Carlos Bandeira, Luana Leandro Gois, Carlos Gustavo Regis Silva, Alice Rousseau, Aurelien Corneau, Nadine Tarantino, Christopher Maucourant, Gabriel Andrade Nonato Queiroz, Vincent Vieillard, Hans Yssel, Gubio Soares Campos, Silvia Sardi, Brigitte Autran, Maria Fernanda Rios Grassi

Analysis of Haemonchus embryos at single cell resolution identifies two eukaryotic elongation factors as intervention target candidates

Computational and Structural Biotechnology Journal · 2024 · journal-article

Neil David Young, Joseph J. Byrne, Túlio de Lima Campos, Bill C. H. Chang, Aya C. Taki

Septo-optic dysplasia: a case report on Morsier syndrome

Residência Pediátrica · 2024 · journal-article

Marina Julio, Brenna Tenorio, Helen Secchin, Juliana Caires de Oliveira Achili Ferreira, Michel Platini Caldas de Souza

The CDR3 region as the major driver of TREM-1 interaction with its ligands, an in silico characterization

Computational and Structural Biotechnology Journal · 2023 · journal-article

Amanda de Oliveira Matos, Pedro Henrique dos Santos Dantas, Mike Contreras, Geraldo R. Sartori, Marcelle Silva‐Sales, João Hermínio Martins da Silva, Bruno Junior Neves, Carolina Horta Andrade, Helioswilton Sales‐Campos

In silico screening of phenylethanoid glycosides, a class of pharmacologically active compounds as natural inhibitors of SARS-CoV-2 proteases

Computational and Structural Biotechnology Journal · 2023 · journal-article

Caio Felipe de Araujo Ribas Cheohen, Maria Eduarda Alves Esteves, Thamirys Silva da Fonseca, Carla Monteiro Leal, Fernanda de Lemos Fernandes Assis, Mariana Freire Campos, Raianne Soares Rebelo, Diego Allonso, Gilda Guimarães Leitão, Manuela Leal da Silva, Suzana Guimarães Leitão

Computational and Structural Biotechnology Journal · 2022 · journal-article

Thiago Peixoto Leal, Vinícius Furlan, Mateus Henrique Gouveia, Julia Maria Saraiva‐Duarte, P.A.S. Fonseca, Rafael Pereira Tou, Marília O. Scliar, Gilderlânio Santana de Araújo, Lucas Ferrari da Costa, Camila Zolini, Maria Gabriela Campolina Diniz Peixoto, Maria Raquel Santos Carvalho, Maria Fernanda Lima‐Costa, Robert H. Gilman, Eduardo Tarazona‐Santos, Maira Ribeiro Rodrigues

Update and elucidation of Plasmodium kinomes: Prioritization of kinases as potential drug targets for malaria

Computational and Structural Biotechnology Journal · 2022 · journal-article

Joyce Villa Verde Bastos Borba, Arthur C. Silva, Marília Nunes do Nascimento, Letícia Tiburcio Ferreira, Aline Rimoldi, Luísa Starling, Pablo Ivan Pereira Ramos, Fábio Trindade Maranhão Costa, Carolina Horta Andrade

ExVe : The knowledge base of orthologous proteins identified in fungal extracellular vesicles

Computational and Structural Biotechnology Journal · 2021 · journal-article

Vinícius da Silva Coutinho Parreira, Letícia Graziela Costa Santos, Márcio Lourenço Rodrigues, Fábio Passetti

Transcriptional and translational landscape of Candida auris in response to caspofungin

Computational and Structural Biotechnology Journal · 2021 · journal-article

Daniel Zamith‐Miranda, Rafaela F. Amatuzzi, Isadora F. Munhoz da Rocha, Sharon T. Martins, Aline Castro Rodrigues Lucena, Alexandre Zanatta Vieira, Gabriel Trentin, Fausto Bruno dos Reis Almeida, Márcio Lourenço Rodrigues, Ernesto Nakayasu, Joshua Daniel Nosanchuk, Lysangela R. Alves

Guidelines To Predict Binding Poses of Antibody–Integrin Complexes

ACS Omega · 2020 · journal-article

Beatriz Chaves, Geraldo R. Sartori, Disraeli C. A. Vasconcelos, Ernesto R. Caffarena, Vinícius Cotta-de-Almeida, João H. M. da Silva

Unveiling the Kinomes of Leishmania infantum and L. braziliensis Empowers the Discovery of New Kinase Targets and Antileishmanial Compounds

Computational and Structural Biotechnology Journal · 2019 · journal-article

Joyce Villa Verde Bastos Borba, Arthur C. Silva, Pablo Ivan Pereira Ramos, Nathália Grazzia, Danilo Ciccone Miguel, Eugene N. Muratov, Nicholas Furnham, Carolina Horta Andrade

Role of lipid transporters in fungal physiology and pathogenicity

Computational and Structural Biotechnology Journal · 2019 · journal-article

Juliana Rizzo, Lyubomir Dimitrov Stanchev, Vanessa K. A. Silva, Leonardo Nimrichter, Thomas Günther Pomorski, Márcio Lourenço Rodrigues

An Evaluation of Machine Learning Approaches for the Prediction of Essential Genes in Eukaryotes Using Protein Sequence-Derived Features

Computational and Structural Biotechnology Journal · 2019 · journal-article

Túlio de Lima Campos, Neil David Young

Bipolar versus unipolar energy in the surgical ablation of atrial fibrillation in patients with mitral valve surgery